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[ CAS No. 57334-36-8 ] {[proInfo.proName]}

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Chemical Structure| 57334-36-8
Chemical Structure| 57334-36-8
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Product Details of [ 57334-36-8 ]

CAS No. :57334-36-8 MDL No. :MFCD00661657
Formula : C9H6ClNO Boiling Point : -
Linear Structure Formula :- InChI Key :DEPRJVQVGXOXRN-UHFFFAOYSA-N
M.W : 179.60 Pubchem ID :384164
Synonyms :

Safety of [ 57334-36-8 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 57334-36-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 57334-36-8 ]

[ 57334-36-8 ] Synthesis Path-Downstream   1~36

  • 1
  • [ 107-85-7 ]
  • [ 57334-36-8 ]
  • 4-isopentylamino-quinolin-8-ol [ No CAS ]
YieldReaction ConditionsOperation in experiment
With phenol at 120 - 125℃;
  • 2
  • [ 57334-36-8 ]
  • [ 111-86-4 ]
  • 4-octylamino-quinolin-8-ol [ No CAS ]
YieldReaction ConditionsOperation in experiment
With phenol at 120 - 125℃;
  • 3
  • [ 57334-36-8 ]
  • [ 111-68-2 ]
  • 4-heptylamino-quinolin-8-ol [ No CAS ]
YieldReaction ConditionsOperation in experiment
With phenol at 120 - 125℃;
  • 4
  • [ 57334-36-8 ]
  • [ 106-47-8 ]
  • 4-(4-chloro-anilino)-quinolin-8-ol; hydrochloride [ No CAS ]
YieldReaction ConditionsOperation in experiment
With ethanol
  • 7
  • [ 57334-36-8 ]
  • [ 109-73-9 ]
  • 4-butylamino-quinolin-8-ol [ No CAS ]
YieldReaction ConditionsOperation in experiment
With phenol at 120 - 125℃;
  • 8
  • [ 57334-36-8 ]
  • [ 100-46-9 ]
  • 4-benzylamino-quinolin-8-ol; hydrochloride [ No CAS ]
YieldReaction ConditionsOperation in experiment
With phenol at 120 - 125℃;
  • 9
  • [ 57334-36-8 ]
  • [ 57334-37-9 ]
YieldReaction ConditionsOperation in experiment
With ammonia; phenol at 160℃;
  • 11
  • [ 7703-74-4 ]
  • [ 57334-36-8 ]
  • [ 97004-37-0 ]
YieldReaction ConditionsOperation in experiment
65% With potassium hydroxide In ethanol; benzene for 4h; Heating;
  • 12
  • [ 57334-36-8 ]
  • [ 817-09-4 ]
  • [ 97032-88-7 ]
YieldReaction ConditionsOperation in experiment
60% With potassium hydroxide In ethanol Heating;
  • 13
  • [ 57334-36-8 ]
  • [ 86045-19-4 ]
  • [ 97032-87-6 ]
YieldReaction ConditionsOperation in experiment
61% With potassium hydroxide In ethanol; benzene for 4h; Heating;
  • 14
  • [ 57334-36-8 ]
  • 4,5-dichloro-8-quinolinol [ No CAS ]
YieldReaction ConditionsOperation in experiment
With N-chloro-succinimide In sulfuric acid Ambient temperature; Yield given;
  • 15
  • [ 57334-36-8 ]
  • 4,5,7-trichloro-8-quinolinol [ No CAS ]
YieldReaction ConditionsOperation in experiment
98% With N-chloro-succinimide In acetic acid at 20℃; for 144h;
  • 16
  • [ 57334-36-8 ]
  • [ 98961-97-8 ]
  • 8-hydroxy-4-[4-(N,N-dimethylsulfamoyl)piperazin-1-yl]quinoline [ No CAS ]
YieldReaction ConditionsOperation in experiment
35% at 130℃; for 4h; Heating;
  • 17
  • [ 57334-36-8 ]
  • [ 97004-39-2 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: 65 percent / KOH / ethanol; benzene / 4 h / Heating 2: 69 percent / methanol / 3 h / Heating
  • 18
  • [ 57334-36-8 ]
  • [ 97004-40-5 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: 61 percent / KOH / ethanol; benzene / 4 h / Heating 2: 68 percent / methanol / 3 h / Heating
  • 19
  • [ 21269-34-1 ]
  • [ 57334-36-8 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: 95 percent / POCl3 / 3 h / Heating 2: 89 percent / 76percent H2SO4
  • 20
  • [ 57334-36-8 ]
  • [ 102660-26-4 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: ethanol 2: ethanol
YieldReaction ConditionsOperation in experiment
790 mg (52%) 56.B B. B. 4-Chloro-quinolin-8-ol A solution of 1.3 g of the hydrobromide salt and 50 mL of water was adjusted to pH 9 by the addition of 4N sodium hydroxide. The resulting precipitate was filtered, washed with water, and air-dried to give 790 mg (52%) of the title compound: m.p. 143°-145° C.
  • 23
  • [ 57334-36-8 ]
  • cobalt(II) chloride hexahydrate [ No CAS ]
  • [ 97057-07-3 ]
YieldReaction ConditionsOperation in experiment
With sodium acetate In ethanol; acetic acid addn. of an excess of quinoline in EtOH at 50°C to a soln. of Co-salt and sodium acetate in aq. acetic acid, 80-90°C, neutralization (aq. NaOH), ppt., filtn., washing (hot H2O), hydrated complex is heated to 130°C for several h; elem. anal.;
  • 24
  • [ 110-89-4 ]
  • [ 57334-36-8 ]
  • [ 1201680-80-9 ]
YieldReaction ConditionsOperation in experiment
95% at 140 - 150℃; for 3h; Neat (no solvent);
  • 25
  • [ 109-01-3 ]
  • [ 57334-36-8 ]
  • [ 1201680-81-0 ]
YieldReaction ConditionsOperation in experiment
88% at 140 - 150℃; for 1h; Neat (no solvent);
  • 26
  • [ 57334-36-8 ]
  • C22H17BrN2O [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1.1: potassium carbonate / N,N-dimethyl-formamide / 0.17 h / 20 °C / Inert atmosphere 1.2: 18 h / 20 °C / Inert atmosphere 2.1: 17 h / 135 °C / Inert atmosphere 2.2: 0.17 h / Reflux
  • 27
  • [ 57334-36-8 ]
  • [ 1338350-01-8 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1.1: potassium carbonate / N,N-dimethyl-formamide / 0.17 h / 20 °C / Inert atmosphere 1.2: 18 h / 20 °C / Inert atmosphere 2.1: 17 h / 135 °C / Inert atmosphere 2.2: 0.17 h / Reflux 3.1: palladium diacetate; potassium carbonate; tricyclohexylphosphine tetrafluoroborate / N,N-dimethyl acetamide / 3 h / 160 °C / Inert atmosphere
  • 28
  • [ 57334-36-8 ]
  • [ 1338350-02-9 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 4 steps 1.1: potassium carbonate / N,N-dimethyl-formamide / 0.17 h / 20 °C / Inert atmosphere 1.2: 18 h / 20 °C / Inert atmosphere 2.1: 17 h / 135 °C / Inert atmosphere 2.2: 0.17 h / Reflux 3.1: palladium diacetate; potassium carbonate; tricyclohexylphosphine tetrafluoroborate / N,N-dimethyl acetamide / 3 h / 160 °C / Inert atmosphere 4.1: palladium 10% on activated carbon; hydrogen / ethanol / 5 h / Reflux
  • 29
  • [ 57334-36-8 ]
  • [ 1338350-03-0 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1.1: 17 h / 135 °C / Inert atmosphere 1.3: 0.25 h / Reflux 2.1: water / 1 h / 20 °C
  • 30
  • [ 57334-36-8 ]
  • [ 1338350-04-1 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1.1: 17 h / 135 °C / Inert atmosphere 1.3: 0.25 h / Reflux 2.1: water / 1 h / 20 °C 3.1: palladium diacetate; potassium carbonate; tricyclohexylphosphine tetrafluoroborate / N,N-dimethyl acetamide / 4 h / 160 °C / Inert atmosphere
  • 31
  • [ 57334-36-8 ]
  • [ 1338350-05-2 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 4 steps 1.1: 17 h / 135 °C / Inert atmosphere 1.3: 0.25 h / Reflux 2.1: water / 1 h / 20 °C 3.1: palladium diacetate; potassium carbonate; tricyclohexylphosphine tetrafluoroborate / N,N-dimethyl acetamide / 4 h / 160 °C / Inert atmosphere 4.1: sodium hydroxide / ethanol; water / 2.5 h / Reflux
  • 32
  • [ 57334-36-8 ]
  • [ 698-19-1 ]
  • C17H15BrN2O [ No CAS ]
  • 33
  • [ 57334-36-8 ]
  • [ 100-39-0 ]
  • [ 26774-12-9 ]
YieldReaction ConditionsOperation in experiment
82% Stage #1: 4-chloro-8-hydroxyquinoline With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.166667h; Inert atmosphere; Stage #2: benzyl bromide In N,N-dimethyl-formamide at 20℃; for 18h; Inert atmosphere;
  • 34
  • [ 14959-84-3 ]
  • [ 57334-36-8 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1: sodium hydroxide / water; acetone / 3 h / 20 °C 2: trichlorophosphate / 1 h / Reflux; Inert atmosphere 3: sodium hydroxide / water; ethanol / 1 h / Reflux
  • 35
  • 4-hydroxyquinolin-8-yl 4-methylbenzenesulfonate [ No CAS ]
  • [ 57334-36-8 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: trichlorophosphate / 1 h / Reflux; Inert atmosphere 2: sodium hydroxide / water; ethanol / 1 h / Reflux
  • 36
  • [ 59-00-7 ]
  • [ 57334-36-8 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 4 steps 1: diphenylether / 2.5 h / 250 °C 2: sodium hydroxide / water; acetone / 3 h / 20 °C 3: trichlorophosphate / 1 h / Reflux; Inert atmosphere 4: sodium hydroxide / water; ethanol / 1 h / Reflux
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