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[ CAS No. 59551-02-9 ]

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2D
Chemical Structure| 59551-02-9
Chemical Structure| 59551-02-9
Structure of 59551-02-9 *Storage: {[proInfo.prStorage]}

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Product Details of [ 59551-02-9 ]

CAS No. :59551-02-9MDL No. :MFCD02752660
Formula : C10H6N2 Boiling Point : -
Linear Structure Formula :-InChI Key :-
M.W :154.17Pubchem ID :-
Synonyms :

Computed Properties of [ 59551-02-9 ]

TPSA : - H-Bond Acceptor Count : -
XLogP3 : - H-Bond Donor Count : -
SP3 : - Rotatable Bond Count : -

Safety of [ 59551-02-9 ]

Signal Word:WarningClass:
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501UN#:
Hazard Statements:H302-H312-H315-H319-H332-H335Packing Group:
GHS Pictogram:

Application In Synthesis of [ 59551-02-9 ]

  • Downstream synthetic route of [ 59551-02-9 ]

[ 59551-02-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1006-50-4 ]
  • [ 544-92-3 ]
  • [ 59551-02-9 ]
YieldReaction ConditionsOperation in experiment
97% In N,N-dimethyl-formamide; for 0.666667h;Reflux; Inert atmosphere; A mixture of <strong>[1006-50-4]5-iodoquinoline</strong> (0.56 g; 2.2 mmol) and CuCN (0.51 g; 5.7 mmol) in anhydrous DMF (3 ml) was refluxed for 40 min under N2. After cooling to room temperature, the mixture was diluted to 20 ml with EtOAc and NaCN (0.75 g; 15.3 mmol) was added followed by H2O (10 ml). The resulting mixture was vigorously stirred for 10 min and organic phase was separated, washed with H2O, brine, dried over anhydrous MgSO4, filtered and filtrate evaporated to dryness to give the title compound (0.33 g; 97%) as colourless solid. 1H-NMR (CDCI3) 7.59 - 7.63 (m, 1 H); 7.78 (m, 1 H); 7.98 (dd, 1 H, J = 3, 6 Hz); 8.36 (d, 1 H, J = 9 Hz); 8.54 (no, 1 H): 9.05 (dd, 1 H, J = 3, 6 Hz).
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