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[ CAS No. 60524-15-4 ]

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2D
Chemical Structure| 60524-15-4
Chemical Structure| 60524-15-4
Structure of 60524-15-4 *Storage: {[proInfo.prStorage]}

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Product Details of [ 60524-15-4 ]

CAS No. :60524-15-4MDL No. :MFCD01860226
Formula : C6H4ClN3O3 Boiling Point : 320.7°C at 760 mmHg
Linear Structure Formula :-InChI Key :-
M.W :201.57Pubchem ID :151622
Synonyms :

Computed Properties of [ 60524-15-4 ]

TPSA : 102 H-Bond Acceptor Count : 4
XLogP3 : 0.5 H-Bond Donor Count : 1
SP3 : 0.00 Rotatable Bond Count : 1

Safety of [ 60524-15-4 ]

Signal Word:WarningClass:N/A
Precautionary Statements:P280-P305+P351+P338UN#:N/A
Hazard Statements:H302Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 60524-15-4 ]

  • Upstream synthesis route of [ 60524-15-4 ]
  • Downstream synthetic route of [ 60524-15-4 ]

[ 60524-15-4 ] Synthesis Path-Upstream   1~9

  • 1
  • [ 135795-55-0 ]
  • [ 60524-15-4 ]
YieldReaction ConditionsOperation in experiment
54.2% With ammonia In water; acetone at 25℃; for 0.166667 h; Synthesis of the compound 22 The compound 21 (8.3 g, 0.04 mol) was added into thionyl chloride (80 mL) and refluxed for 3 h. The thionyl chloride was evaporated off, the acetone (240 mL) was added and stirred at 25°C, aqua ammoniae was added dropwise, and the reaction was run for 10 min before completed. The filtrate was concentrated to a quarter of the total volume, and the remaining concentrated solution was poured into 200g of broken ice, 4.5g of a yellow solid product was precipitated with a yield of 54.2percent. The melting point is 177.3-178.2 °C.
Reference: [1] Russian Chemical Bulletin, 2005, vol. 54, # 8, p. 1907 - 1914
[2] Patent: EP2366691, 2011, A1, . Location in patent: Page/Page column 10
[3] Antimicrobial Agents and Chemotherapy, 2014, vol. 58, # 1, p. 55 - 60
  • 2
  • [ 609-71-2 ]
  • [ 60524-15-4 ]
Reference: [1] Russian Chemical Bulletin, 2005, vol. 54, # 8, p. 1907 - 1914
  • 3
  • [ 6854-07-5 ]
  • [ 60524-15-4 ]
Reference: [1] Russian Chemical Bulletin, 2005, vol. 54, # 8, p. 1907 - 1914
  • 4
  • [ 42959-38-6 ]
  • [ 60524-15-4 ]
Reference: [1] Patent: EP2366691, 2011, A1,
  • 5
  • [ 1603-40-3 ]
  • [ 60524-15-4 ]
Reference: [1] Patent: EP2366691, 2011, A1,
  • 6
  • [ 21901-34-8 ]
  • [ 60524-15-4 ]
Reference: [1] Patent: EP2366691, 2011, A1,
  • 7
  • [ 22280-56-4 ]
  • [ 60524-15-4 ]
Reference: [1] Patent: EP2366691, 2011, A1,
  • 8
  • [ 10128-92-4 ]
  • [ 60524-15-4 ]
Reference: [1] Antimicrobial Agents and Chemotherapy, 2014, vol. 58, # 1, p. 55 - 60
  • 9
  • [ 941083-49-4 ]
  • [ 60524-15-4 ]
Reference: [1] Antimicrobial Agents and Chemotherapy, 2014, vol. 58, # 1, p. 55 - 60
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