Alternatived Products of [ 61886-26-8 ]
Product Details of [ 61886-26-8 ]
CAS No. : | 61886-26-8 |
MDL No. : | MFCD00089429 |
Formula : |
C12H18N2O2S
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
254.35
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 61886-26-8 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 61886-26-8 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 61886-26-8 ]
- 1
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[ 93125-79-2 ]
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[ 61886-26-8 ]
Yield | Reaction Conditions | Operation in experiment |
48% |
With palladium on activated charcoal; hydrogen In methanol at 20℃; for 1h; |
|
Reference:
[1]Vandyck, Koen; Rombouts, Geert; Stoops, Bart; Tahri, Abdellah; Vos, Ann; Verschueren, Wim; Wu, Yiming; Yang, Jingmei; Hou, Fuliang; Huang, Bing; Vergauwen, Karen; Dehertogh, Pascale; Berke, Jan Martin; Raboisson, Pierre
[Journal of Medicinal Chemistry, 2018, vol. 61, # 14, p. 6247 - 6260]
- 2
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[ 61886-26-8 ]
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[ 65-85-0 ]
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[ 2230755-70-9 ]
Yield | Reaction Conditions | Operation in experiment |
36.4% |
Stage #1: 3-amino-N-cyclohexylbenzenesulfonamide; benzoic acid With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; |
|
Reference:
[1]Vandyck, Koen; Rombouts, Geert; Stoops, Bart; Tahri, Abdellah; Vos, Ann; Verschueren, Wim; Wu, Yiming; Yang, Jingmei; Hou, Fuliang; Huang, Bing; Vergauwen, Karen; Dehertogh, Pascale; Berke, Jan Martin; Raboisson, Pierre
[Journal of Medicinal Chemistry, 2018, vol. 61, # 14, p. 6247 - 6260]
- 3
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[ 456-22-4 ]
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[ 61886-26-8 ]
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[ 2346740-64-3 ]
Yield | Reaction Conditions | Operation in experiment |
29% |
Stage #1: 4-Fluorobenzoic acid; 3-amino-N-cyclohexylbenzenesulfonamide With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; |
|
Reference:
[1]Vandyck, Koen; Rombouts, Geert; Stoops, Bart; Tahri, Abdellah; Vos, Ann; Verschueren, Wim; Wu, Yiming; Yang, Jingmei; Hou, Fuliang; Huang, Bing; Vergauwen, Karen; Dehertogh, Pascale; Berke, Jan Martin; Raboisson, Pierre
[Journal of Medicinal Chemistry, 2018, vol. 61, # 14, p. 6247 - 6260]
- 4
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[ CAS Unavailable ]
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[ 61886-26-8 ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 2 steps
1: triethylamine / tetrahydrofuran / 20 °C
2: palladium on activated charcoal; hydrogen / methanol / 1 h / 20 °C / 760.05 Torr |
|
Reference:
[1]Vandyck, Koen; Rombouts, Geert; Stoops, Bart; Tahri, Abdellah; Vos, Ann; Verschueren, Wim; Wu, Yiming; Yang, Jingmei; Hou, Fuliang; Huang, Bing; Vergauwen, Karen; Dehertogh, Pascale; Berke, Jan Martin; Raboisson, Pierre
[Journal of Medicinal Chemistry, 2018, vol. 61, # 14, p. 6247 - 6260]
- 5
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[ 121-51-7 ]
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[ 61886-26-8 ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 2 steps
1: triethylamine / tetrahydrofuran / 20 °C
2: palladium on activated charcoal; hydrogen / methanol / 1 h / 20 °C / 760.05 Torr |
|
Reference:
[1]Vandyck, Koen; Rombouts, Geert; Stoops, Bart; Tahri, Abdellah; Vos, Ann; Verschueren, Wim; Wu, Yiming; Yang, Jingmei; Hou, Fuliang; Huang, Bing; Vergauwen, Karen; Dehertogh, Pascale; Berke, Jan Martin; Raboisson, Pierre
[Journal of Medicinal Chemistry, 2018, vol. 61, # 14, p. 6247 - 6260]
- 6
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[ 13139-15-6 ]
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[ 61886-26-8 ]
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[ 2912521-75-4 ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 2 steps
1: N-[3-(N,N-dimethylamino)-propyl]-N'-ethyl-carbodiimide hydrochloride; benzotriazol-1-ol / tetrahydrofuran / 20 °C
2: trifluoroacetic acid / dichloromethane / 4 h / 20 °C |
|
Reference:
[1]Luo, Jinghan; Wu, Chengjun; Hu, Yanjun; Jia, Xingxing; Chen, Yu; Sun, Tiemin
[New Journal of Chemistry, 2022, vol. 46, # 9, p. 4142 - 4155]
- 7
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[ 13139-15-6 ]
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[ 61886-26-8 ]
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[ 2912521-54-9 ]
Yield | Reaction Conditions | Operation in experiment |
|
With benzotriazol-1-ol; N-[3-(N,N-dimethylamino)-propyl]-N'-ethyl-carbodiimide hydrochloride In tetrahydrofuran at 20℃; |
|
Reference:
[1]Luo, Jinghan; Wu, Chengjun; Hu, Yanjun; Jia, Xingxing; Chen, Yu; Sun, Tiemin
[New Journal of Chemistry, 2022, vol. 46, # 9, p. 4142 - 4155]