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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 63-92-3 Chemical Structure| 63-92-3

Structure of Phenoxybenzamine HCl
CAS No.: 63-92-3

Chemical Structure| 63-92-3

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Phenoxybenzamine HCl is a non-selective irreversible dibenzamine α adrenergic antagonist with antihypertensive and vasodilatory properties.

Synonyms: Phenoxybenzamine (hydrochloride); NSC 37448; NCI-c01661

4.5 *For Research Use Only !

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Product Details of Phenoxybenzamine HCl

CAS No. :63-92-3
Formula : C18H23Cl2NO
M.W : 340.29
SMILES Code : CC(N(CC1=CC=CC=C1)CCCl)COC2=CC=CC=C2.[H]Cl
Synonyms :
Phenoxybenzamine (hydrochloride); NSC 37448; NCI-c01661
MDL No. :MFCD00055152
InChI Key :VBCPVIWPDJVHAN-UHFFFAOYSA-N
Pubchem ID :5284441

Safety of Phenoxybenzamine HCl

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H350
Precautionary Statements:P264-P270-P301+P312-P330-P501-P201-P202-P308+P313
Class:6.1
UN#:2811
Packing Group:

Related Pathways of Phenoxybenzamine HCl

GPCR

Isoform Comparison

Biological Activity

Target
  • α-adrenergic receptor

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT03176693 Pheochromocytoma ... More >> Paraganglioma Less << Phase 3 Recruiting May 2024 United States, California ... More >> University of California, Los angeles Recruiting Los Angeles, California, United States, 90025 Principal Investigator: Masha J Livhits, MD          Sub-Investigator: Eric J Kuo, MD Less <<
NCT00569855 - Completed - -
NCT00569855 Open-heart Surgery ... More >> Cardiopulmonary Bypass Less << Phase 2 Completed - United States, Arkansas ... More >> Arkansas Children's Hospital Little Rock, Arkansas, United States, 72207 Less <<
NCT00620945 Congenital Heart Surgery ... More >> Cardiopulmonary Bypass Less << Not Applicable Terminated(New protocol now be... More >>ing used for cardiopulmonary bypass) Less << - -
NCT00620945 - Terminated(New protocol now be... More >>ing used for cardiopulmonary bypass) Less << - -
NCT00770705 Congenital Heart Disease Phase 2 Withdrawn(poor enrollment) - United States, Tennessee ... More >> Vanderbilt Children's Hospital Nashville, Tennessee, United States, 37232 Less <<
NCT01379898 Pheochromocytoma Phase 4 Completed - Netherlands ... More >> Department of Endocrinology, University Medical Center Groningen Groningen, Netherlands, 9700 RB Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.94mL

0.59mL

0.29mL

14.69mL

2.94mL

1.47mL

29.39mL

5.88mL

2.94mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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