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Chemical Structure| 681282-09-7 Chemical Structure| 681282-09-7

Structure of MYCMI-6
CAS No.: 681282-09-7

Chemical Structure| 681282-09-7

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MYCMI-6 (NSC354961) is a potent and selective endogenous MYC:MAX protein interactions inhibitor. MYCMI-6 blocks MYC-driven transcription and binds selectively to the MYC bHLHZip domain with a Kd of 1.6 μM. MYCMI-6 inhibits tumor cell growth in a MYC-dependent manner (IC50<0.5 μM). MYCMI-6 is not cytotoxic to normal human cells. MYCMI-6 induces apoptosis .

Synonyms: NSC354961

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Product Details of MYCMI-6

CAS No. :681282-09-7
Formula : C20H19N7O
M.W : 373.41
SMILES Code : NC1=NC(N)=CC=C1/N=N/C2=CC3=NC4=CC=C(OCC)C=C4C(N)=C3C=C2
Synonyms :
NSC354961
MDL No. :MFCD32701920
InChI Key :QNWGRUNKGVWOTA-UHFFFAOYSA-N
Pubchem ID :434695

Safety of MYCMI-6

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of MYCMI-6

cytoskeleton
Hedgehog

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.68mL

0.54mL

0.27mL

13.39mL

2.68mL

1.34mL

26.78mL

5.36mL

2.68mL

Dissolving Methods
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

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