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Chemical Structure| 68573-24-0 Chemical Structure| 68573-24-0

Structure of N-(p-Coumaroyl) Serotonin
CAS No.: 68573-24-0

Chemical Structure| 68573-24-0

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N-(p-Coumaroyl) Serotonin is a polyphenol isolated from safflower seeds with antioxidant and anti-atherosclerotic properties, useful for cardiovascular disease and atherosclerosis research. N-(p-Coumaroyl) Serotonin inhibits PDGF-induced on phosphorylation of PDGF receptor and Ca2+ release from sarcoplasmic reticulum.

Synonyms: NSC 369503; p-coumaroylserotonin

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Product Details of N-(p-Coumaroyl) Serotonin

CAS No. :68573-24-0
Formula : C19H18N2O3
M.W : 322.36
SMILES Code : OC(C=C12)=CC=C2NC=C1CCNC(C=CC3=CC=C(O)C=C3)=O
Synonyms :
NSC 369503; p-coumaroylserotonin
MDL No. :MFCD09840280
InChI Key :WLZPAFGVOWCVMG-FPYGCLRLSA-N
Pubchem ID :5458879

Safety of N-(p-Coumaroyl) Serotonin

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Related Pathways of N-(p-Coumaroyl) Serotonin

RTK

Isoform Comparison

Biological Activity

Description
N-(p-Coumaroyl) Serotonin is a polyphenol extracted from safflower seeds, possessing antioxidative, anti-atherogenic, and anti-inflammatory characteristics. It acts by inhibiting PDGF-induced phosphorylation of the PDGF receptor and Ca2+ release from the sarcoplasmic reticulum [1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.10mL

0.62mL

0.31mL

15.51mL

3.10mL

1.55mL

31.02mL

6.20mL

3.10mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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