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Good results are obtained when using a solution which contains one or more of the compounds and/or their salts from the group ... 2,4-dihydroxybenzohydroxamic acid 3,5-methoxy-N-methyl-benzohydroxamic acid 2,4-dihydroxybenzohydroxamic acid 2,3-dihydroxybenzohydroxamic acid 3,4-dihydroxybenzohydroxamic acid 3,4,5-trimethoxy-benzohydroxamic acid 3,4,5-trimethoxy-N-methyl-benzohydroxamic acid 4-hydroxy-3-methoxy-benzohydroxamic acid ...
Solution according to one of the previous claims, which contains one or more of the compounds and/or their salts from the group ... 2,4-dihydroxybenzohydroxamic acid 3,5-dimethoxy-N-methyl-benzohydroxamic acid 2,4-dihydroxybenzohydroxamic acid 2,3-dihydroxybenzohydroxamic acid 3,4-dihydroxybenzohydroxamic acid 3,4,5-trimethoxy-benzohydroxamic acid 3,4,5-trimethoxy-N-methyl-benzohydroxamic acid 4-hydroxy-3-methoxy-benzohydroxamic acid ...
Compounds illustrative of the above formula include: ... 3,4,5-trihydroxybenzohydroxamic acid 2,3,5-trihydroxybenzohydroxamic acid 2,3,6-trihydroxybenzohydroxamic acid 2,3-dihydroxybenzohydroxamic acid 3,4-dihydroxybenzohydroxamic acid N-ethyl 3,4,5-trihydroxybenzamide 3,4-dihydroxyphenylacetic acid 3,4,5-trihydroxyphenylacetic acid ...
Compound of this invention with vicinal hydroxy include in addition ... 2,3,5-trihydroxybenzohydroxamic acid; 2,4,5-trihydroxybenzohydroxamic acid; 2,3,6-trihydroxybenzohydroxamic acid; 2,3-dihydroxybenzohydroxamic acid; 3,4-dihydroxybenzohydroxamic acid; N-methyl 2,3,4-trihydroxybenzamide; N-ethyl 3,4,5-trihydroxybenzamide; N-n-propyl 3,4-dihydroxybenzamide;
Illustrative compounds useful in our novel method include the following benzohydroxamic acids, benzamides or phenyl hydroxybenzoates: ... 2,4,6-trihydroxybenzohydroxamic acid; N-ethyl 3,4,5-trihydroxybenzamide. 2,3,4-trihydroxybenzohydroxamic acid; 3,4,5-trihydroxybenzohydroxamic acid; 3,4-dihydroxybenzohydroxamic acid; 2,3,5-trihydroxybenzohydroxamic acid; 2,4,5-trihydroxybenzohydroxamic acid; 2,3,6-trihydroxybenzohydroxamic acid; ...
Illustrative compounds useful in our novel method include the following benzohydroxamic acids, benzamides or phenyl hydroxybenzoates, compounds according to I wherein m is 0; ... phenyl 3,4,5-trihydroxybenzoate (phenyl gallate); phenyl 2,4,6-trihydroxybenzoate; N-ethyl 3,4,5-trihydroxybenzamide. 2,3,4-trihydroxybenzohydroxamic acid; 3,4-dihydroxybenzohydroxamic acid; 3,4,5-trihydroxybenzohydroxamic acid; 3,5-dihydroxybenzohydroxamic acid; phenyl 2,3,4-trihydroxybenzoate; ...
A mixture of 391 mg Platinum and 169.87 mg of silver nitrate were dissolved in 10 ml of DMF, and the reaction was carried out for 24 hours to remove silver chloride Starch, the supernatant is solution one; 42.3 mg of 3,4-dihydroxybenzenamic acid was mixed with 80 mg of sodium hydroxide, After the reaction to remove the insoluble material, the supernatant for the solution two; solution 1 and solution two mixed reaction 48h, remove the organic solvent, dissolved with methanol to remove excess picoline, recrystallization to get amphiphilic drug - drug complex; Its structure (e) is as follows:
300 mg of cisplatin and 169.87 mg of silver nitrate were dissolved in 10 mL of DMF, 24 hours after the reaction to remove silver chloride precipitation, the supernatant for the solution one; 42.3 mg of 3,4-dihydroxybenzenamic acid was mixed with 35.3 mg of sodium carbonate in 5 mL of DMF, After the reaction to remove the insoluble material, the supernatant for the solution two; solution 1 and solution two mixed reaction 48h, Removing the organic solvent, dissolving with methanol to remove excess cisplatin, and recrystallizing to obtain an amphiphilic drug-drug complex,Its structure (c) is as follows;
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