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Chemical Structure| 714971-87-6 Chemical Structure| 714971-87-6

Structure of RO0711401
CAS No.: 714971-87-6

Chemical Structure| 714971-87-6

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RO0711401 is an NMDA receptor antagonist that modulates glutamate signaling by blocking NMDA receptors, showing antidepressant and neuroprotective effects by alleviating excitatory neurotransmission in the central nervous system.

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Product Details of RO0711401

CAS No. :714971-87-6
Formula : C18H11F3N2O3
M.W : 360.29
SMILES Code : O=C(NC1OC=C(C(F)(F)F)N=1)C1C2C=CC=CC=2OC2C=CC=CC1=2
MDL No. :MFCD31692711
InChI Key :GSGDLBUOSWGZER-UHFFFAOYSA-N
Pubchem ID :10338547

Safety of RO0711401

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of RO0711401

GPCR

Isoform Comparison

Biological Activity

Description
RO0711401 is a selective, orally bioavailable positive allosteric modulator of the mGlu1 receptor, demonstrating an EC50 of 56 nM[1][2].

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Bio Calculators
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2.78mL

0.56mL

0.28mL

13.88mL

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1.39mL

27.76mL

5.55mL

2.78mL

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