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Chemical Structure| 733750-99-7 Chemical Structure| 733750-99-7

Structure of AR 231453
CAS No.: 733750-99-7

Chemical Structure| 733750-99-7

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AR 231453 is a potent and selective small molecule agonist of GPR119 that enhances glucose-dependent insulin secretion and glucagon-like peptide 1 (GLP-1) release, used as an antidiabetic agent.

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Product Details of AR 231453

CAS No. :733750-99-7
Formula : C21H24FN7O5S
M.W : 505.52
SMILES Code : O=[N+](C1=C(N2CCC(C3=NC(C(C)C)=NO3)CC2)N=CN=C1NC4=CC=C(S(=O)(C)=O)C=C4F)[O-]
MDL No. :MFCD14706714
InChI Key :DGBKNTVAKIFYNU-UHFFFAOYSA-N
Pubchem ID :24939268

Safety of AR 231453

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of AR 231453

GPCR

Isoform Comparison

Biological Activity

Description
AR 231453 is a potent, specific and orally available GPR119 agonist. AR 231453 can stimulate β-cell replication and improve islet graft function s[1].[2].

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Bio Calculators
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1 mM

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1.98mL

0.40mL

0.20mL

9.89mL

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0.99mL

19.78mL

3.96mL

1.98mL

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