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Chemical Structure| 761437-28-9 Chemical Structure| 761437-28-9

Structure of NVP-TAE 226
CAS No.: 761437-28-9

Chemical Structure| 761437-28-9

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NVP-TAE 226 is a potent FAK inhibitor with IC50 of 5.5 nM, modestly potent to Pyk2 (IC50=3.5 nM) and 10- to 100-fold less potent against InsR, IGF-1R, ALK, and c-Met.

Synonyms: TAE226

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Product Details of NVP-TAE 226

CAS No. :761437-28-9
Formula : C23H25ClN6O3
M.W : 468.94
SMILES Code : O=C(NC)C1=CC=CC=C1NC2=NC(NC3=CC=C(N4CCOCC4)C=C3OC)=NC=C2Cl
Synonyms :
TAE226
MDL No. :MFCD12031516
InChI Key :UYJNQQDJUOUFQJ-UHFFFAOYSA-N
Pubchem ID :9934347

Safety of NVP-TAE 226

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of NVP-TAE 226

RTK
cytoskeleton

Isoform Comparison

Biological Activity

Target
  • FAK

    FAK, IC50:5.5 nM

    PYK2, IC50:3.5 nM

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.13mL

0.43mL

0.21mL

10.66mL

2.13mL

1.07mL

21.32mL

4.26mL

2.13mL

 

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