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[ CAS No. 769965-95-9 ]

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2D
Chemical Structure| 769965-95-9
Chemical Structure| 769965-95-9
Structure of 769965-95-9 *Storage: {[proInfo.prStorage]}

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Product Details of [ 769965-95-9 ]

CAS No. :769965-95-9MDL No. :MFCD13195329
Formula : C10H8FNO Boiling Point : 351.8±42.0°C at 760 mmHg
Linear Structure Formula :-InChI Key :N/A
M.W :177.18Pubchem ID :58398965
Synonyms :

Computed Properties of [ 769965-95-9 ]

TPSA : - H-Bond Acceptor Count : -
XLogP3 : - H-Bond Donor Count : -
SP3 : - Rotatable Bond Count : -

Safety of [ 769965-95-9 ]

Signal Word:WarningClass:N/A
Precautionary Statements:P261-P305+P351+P338UN#:N/A
Hazard Statements:H302-H315-H319-H335Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 769965-95-9 ]

  • Downstream synthetic route of [ 769965-95-9 ]

[ 769965-95-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 769965-95-9 ]
  • 5’-fluorospiro[cyclopropane-1,3’-indoline] [ No CAS ]
YieldReaction ConditionsOperation in experiment
With lithium aluminium tetrahydride; at 0 - 50℃; for 3.25h; A sample of <strong>[769965-95-9]5-fluoro-siprocyclopropyloxindole</strong> (172 mg, 97 jimol) was cooled in an ice/water bath and treated with a 1.0 M solution of LAH (1.94 ml, 1.9 mmol). The reaction was stirred at room temperature for 15 minutes and then at 50 C for 3 hours and finally was cooled back down with an icelwater bath. The reaction was treated with 1 M NaOH (1.9 mL) followed by water (1.9 mL). The reaction was filtered over celite and dried over MgS04. After filtration, the solvent was removed and the crude material of 5-fluoro- siprocyclopropylindoline was used without purification.
With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 50℃; for 3h; A sample of <strong>[769965-95-9]5-fluoro-siprocyclopropyloxindole</strong> (172 mg, 97 NMOL) was cooled in an ice/water bath and treated with a 1.0 M solution of LAH (1.94 ml, 1.9 mmol). The reaction was stirred at room temperature for 15 minutes and then at 50 C for 3 hours and finally was cooled back down with an ICE/WATER bath. The reaction was treated with 1 M NAOH (1.9 mL) followed by water (1.9 mL). The reaction was filtered over celite and dried over MGS04. After filtration, the solvent was removed and the crude material of 5-fluoro- siprocyclopropylindoline was used without purification.
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