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Chemical Structure| 78-41-1 Chemical Structure| 78-41-1

Structure of Triparanol
CAS No.: 78-41-1

Chemical Structure| 78-41-1

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Triparanol (NSC-65345) is an effective inhibitor of cholesterol biosynthesis, which can block 24- dehydrocholesterol reductase (24-DHCR). Triparanol interferes with the post-translational modification of Hedgehog signal molecule and the sterol sensing domain of its receptor PTCH1, which leads to the down-regulation of Hh signal. Triparanol is also an antihyperlipidemic agent, and it also inhibits the growth of human tumors.

Synonyms: MER-29; NSC 65345

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Product Details of Triparanol

CAS No. :78-41-1
Formula : C27H32ClNO2
M.W : 438.00
SMILES Code : ClC(C=C1)=CC=C1CC(C2=CC=C(OCCN(CC)CC)C=C2)(C3=CC=C(C)C=C3)O
Synonyms :
MER-29; NSC 65345
MDL No. :MFCD00865748

Safety of Triparanol

Isoform Comparison

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Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.28mL

0.46mL

0.23mL

11.42mL

2.28mL

1.14mL

22.83mL

4.57mL

2.28mL

 

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