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[ CAS No. 78790-76-8 ]

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2D
Chemical Structure| 78790-76-8
Chemical Structure| 78790-76-8
Structure of 78790-76-8 *Storage: {[proInfo.prStorage]}

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Product Details of [ 78790-76-8 ]

CAS No. :78790-76-8MDL No. :MFCD23617692
Formula : C13H10N2O Boiling Point : -
Linear Structure Formula :-InChI Key :N/A
M.W :210.23Pubchem ID :10822341
Synonyms :

Computed Properties of [ 78790-76-8 ]

TPSA : - H-Bond Acceptor Count : -
XLogP3 : - H-Bond Donor Count : -
SP3 : - Rotatable Bond Count : -

Safety of [ 78790-76-8 ]

Signal Word:WarningClass:N/A
Precautionary Statements:P280-P305+P351+P338-P310UN#:N/A
Hazard Statements:H302-H315-H319-H332-H335Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 78790-76-8 ]

  • Downstream synthetic route of [ 78790-76-8 ]

[ 78790-76-8 ] Synthesis Path-Downstream   1~7

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YieldReaction ConditionsOperation in experiment
Reference Production Example 74 A mixture of 0.59 g of 60% sodium hydride (in oil) and 5 ml of DMF was stirred while ice-cooling. To the reaction mixture, 1.59 g of benzyl alcohol was added. The reaction mixture was stirred at the same temperature for 10 minutes. To the reaction mixture, 2.0 g of <strong>[68325-15-5]3-chloro<strong>[68325-15-5]isonicotinonitrile</strong></strong> was added, and the reaction mixture was stirred at the same temperature for 30 minutes and at room temperature for 1.5 hours. The reaction mixture was concentrated under reduced pressure, and then to ethyl acetate was added to the reaction mixture, followed by filtration of insoluble matters. The filtrate was concentrated under reduced pressure and the resultant residue was subjected to silica gel column chromatography to give 2.64 g of 3-benzyloxy <strong>[68325-15-5]isonicotinonitrile</strong>. [Show Image] 1H-NMR (CDCl3) delta: 8.52 (s, 1H), 8.36 (d, J=4.6 Hz, 1H), 7.48-7.33 (m, 6H), 5.33 (s, 2H)
Reference Production Example 74 A mixture of 0.59 g of 60% sodium hydride (in oil) and 5 ml of DMF was stirred while ice-cooling. To the reaction mixture, 1.59 g of benzyl alcohol was added. The reaction mixture was stirred at the same temperature for 10 minutes. To the reaction mixture, 2.0 g of <strong>[68325-15-5]3-chloro<strong>[68325-15-5]isonicotinonitrile</strong></strong> was added, and the reaction mixture was stirred at the same temperature for 30 minutes and at room temperature for 1.5 hours. The reaction mixture was concentrated under reduced pressure, and then to ethyl acetate was added to the reaction mixture, followed by filtration of insoluble matters. The filtrate was concentrated under reduced pressure and the resultant residue was subjected to silica gel column chromatography to give 2.64 g of 3-benzyloxy <strong>[68325-15-5]isonicotinonitrile</strong>.1H-NMR (CDCl3) delta: 8.52 (s, 1H), 8.36 (d, J=4.6 Hz, 1H), 7.48-7.33 (m, 6H), 5.33 (s, 2H)
Reference Production Example 74A mixture of 0.59 g of 60% sodium hydride (in oil) and 5 ml of DMF was stirred while ice-cooling. To the reaction mixture, 1.59 g of benzyl alcohol was added. The reaction mixture was stirred at the same temperature for 10 minutes. To the reaction mixture, 2.0 g of <strong>[68325-15-5]3-chloro<strong>[68325-15-5]isonicotinonitrile</strong></strong> was added, and the reaction mixture was stirred at the same temperature for 30 minutes and at room temperature for 1.5 hours. The reaction mixture was concentrated under reduced pressure, and then to ethyl acetate was added to the reaction mixture, followed by filtration of insoluble matters. The filtrate was concentrated under reduced pressure and the resultant residue was subjected to silica gel column chromatography to give 2.64 g of 3-benzyloxy <strong>[68325-15-5]isonicotinonitrile</strong>.-NMR (CDCI3) delta: 8.52 (s, 1H), 8.36 (d, J=4.6 Hz, 1H), 7.48-7.33 (m, 6H), 5.33 (s, 2H)
A mixture of 0.59 g of 60% sodium hydride (in oil) and 5 ml of DMF was stirred while ice-cooling. To the reaction mixture, 1.59 g of benzyl alcohol was added. The reaction mixture was stirred at the same temperature for 10 minutes. To the reaction mixture, 2.0 g of <strong>[68325-15-5]3-chloro<strong>[68325-15-5]isonicotinonitrile</strong></strong> was added, and the reaction mixture was stirred at the same temperature for 30 minutes and at room temperature for 1.5 hours. The reaction mixture was concentrated under reduced pressure, and then to ethyl acetate was added to the reaction mixture, followed by filtration of insoluble matters. The filtrate was concentrated under reduced pressure and the resultant residue was subjected to silica gel column chromatography to give 2.64 g of 3-benzyloxy <strong>[68325-15-5]isonicotinonitrile</strong>.1 H-NMR (CDC13) delta: 8.52 (s, IH), 8.36 (d, J=4.6 Hz, IH), 7.48-7.33 (m, 6H), 5.33 (s, 2H)
A mixture of 0.59 g of 60% sodium hydride (in oil) and 5 ml of DMF was stirred while ice-cooling. To the reaction mixture, 1.59 g of benzyl alcohol was added. The reaction mixture was stirred at the same temperature for 10 minutes. To the reaction mixture, 2.0 g of <strong>[68325-15-5]3-chloro<strong>[68325-15-5]isonicotinonitrile</strong></strong> was added, and the reaction mixture was stirred at the same temperature for 30 minutes and at room temperature for 1.5 hours. The reaction mixture was concentrated under reduced pressure, and then to ethyl acetate was added to the reaction mixture, followed by filtration of insoluble matters. The filtrate was concentrated under reduced pressure and the resultant residue was subjected to silica gel column chromatography to give 2.64 g of 3-benzyloxy <strong>[68325-15-5]isonicotinonitrile</strong>.1H-NMR (CDC13) 6: 8.52 (s, 1H), 8.36 (d, J=4.6 Hz, 1H), 7.48-7.33 (m, 6H), 5.33 (s, 2H)
Reference Production Example 74A mixture of 0.59 g of 60% sodium hydride (in oil) and 5 ml of DMF was stirred while ice-cooling. To the reaction mixture, 1.59 g of benzyl alcohol was added. The reaction mixture was stirred at the same temperature for 10 minutes. To the reaction mixture, 2.0 g of <strong>[68325-15-5]3-chloro<strong>[68325-15-5]isonicotinonitrile</strong></strong> was added, and the reaction mixture was stirred at the same temperature for 30 minutes and at room temperature for 1.5 hours. The reaction mixture was concentrated under reduced pressure, and then to ethyl acetate was added to the reaction mixture, followed by filtration of insoluble matters. The filtrate was concentrated under reduced pressure and the resultant residue was subjected to silica gel column chromatography to give 2.64 g of 3-benzyloxy <strong>[68325-15-5]isonicotinonitrile</strong>.H-NMR (CDC13) 6: 8.52 (s, IH), 8.36 (d, J=4.6 Hz, IH), 7.48-7.33 (m, 6H), 5.33 (s, 2H)
Reference Production Example 74A mixture of 0.59 g of 60% sodium hydride (in oil) and 5 ml of DMF was stirred while ice-cooling. To the reaction mixture, 1.59 g of benzyl alcohol was added. The reaction mixture was stirred at the same temperature for 10 minutes. To the reaction mixture, 2.0 g of <strong>[68325-15-5]3-chloro<strong>[68325-15-5]isonicotinonitrile</strong></strong> was added, and the reaction mixture was stirred at the same temperature for 30 minutes and at room temperature for 1.5 hours. The reaction mixture was concentrated under reduced pressure, and then to ethyl acetate was added to the reaction mixture, followed by filtration of insoluble matters. The filtrate was concentrated under reduced pressure and the resultant residue was subjected to silica gel column chromatography to give 2.64 g of 3-benzyloxy <strong>[68325-15-5]isonicotinonitrile</strong>. 1 H-NMR (CDC13) delta: 8.52 (s, IH), 8.36 (d, J=4.6 Hz, IH), 7.48-7.33 (m, 6H), 5.33 (s, 2H)

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  • 2-phenoxy-3,4-dihydro-1-oxa-3,7-diaza-2-phospha-naphthalene 2-oxide [ No CAS ]
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  • bis-(2-chloro-ethyl)-(2-oxo-3,4-dihydro-2<i>H</i>-1-oxa-3,7-diaza-2λ5-phospha-naphthalen-2-yl)-amine [ No CAS ]
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  • 2-(4-chloro-3-methyl-phenoxy)-3,4-dihydro-1-oxa-3,7-diaza-2-phospha-naphthalene 2-oxide [ No CAS ]
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