Structure of A-7 HCl
CAS No.: 79127-24-5
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
A-7 HCl is a potent calmodulin antagonist.
Synonyms: Ophobolin A; A-7 (hydrochloride)
4.5
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CAS No. : | 79127-24-5 |
Formula : | C20H29ClN2O2S.HCl |
M.W : | 433.44 |
SMILES Code : | Cl.NCCCCCCCCCCNS(=O)(=O)C1=C2C=CC=C(Cl)C2=CC=C1 |
Synonyms : |
Ophobolin A; A-7 (hydrochloride)
|
MDL No. : | MFCD00209822 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT00796302 | - | Completed | - | - | |
NCT00150592 | Attention Deficit Disorder Wit... More >>h Hyperactivity Less << | Phase 2 | Completed | - | - |
NCT00150592 | - | Completed | - | - | |
NCT00796302 | Attention Deficit Disorder Wit... More >>h Hyperactivity Less << | Phase 4 | Completed | - | United States, New York ... More >> State University of New York Stony Brook Stony Brook, New York, United States, 11794 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44106 Ohio State University Nisonger Center Columbus, Ohio, United States, 43210 United States, Pennsylvania University of Pittsburgh Pittsburgh, Pennsylvania, United States, 15213 Less << |
NCT00937040 | Attention Deficit Disorder Wit... More >>h Hyperactivity Less << | Phase 4 | Completed | - | - |
NCT01012622 | Attention Deficit Disorder Wit... More >>h Hyperactivity Less << | Phase 4 | Completed | - | - |
NCT03710642 | Alzheimer's Disease ... More >> Disruptive Behavior Less << | Phase 2 | Recruiting | December 31, 2022 | United States, California ... More >> University of Southern California Not yet recruiting Los Angeles, California, United States, 90033 University of California, San Diego (UCSD) Not yet recruiting San Diego, California, United States, 92093 Stanford University Not yet recruiting Stanford, California, United States, 94305 United States, Kentucky University of Kentucky Recruiting Lexington, Kentucky, United States, 40506 Contact: Amir Elbiheary 859-218-3775 ael243@uky.edu Principal Investigator: Ronan Murphy, MD United States, South Carolina Roper St. Francis Not yet recruiting Charleston, South Carolina, United States, 29401 United States, Texas University of Texas, Southwestern MC at Dallas Not yet recruiting Dallas, Texas, United States, 75390 United States, Washington University of Washington Not yet recruiting Seattle, Washington, United States, 98108 Less << |
NCT00937040 | - | Completed | - | - | |
NCT01012622 | - | Completed | - | - | |
NCT00833794 | - | Completed | - | - | |
NCT00478881 | Overactive Bladder ... More >> Detrusor Overactivity Less << | Phase 2 | Completed | - | - |
NCT00478881 | - | Completed | - | - | |
NCT00833794 | Pain Osteoart... More >>hritis Less << | Phase 3 | Completed | - | - |
NCT01614912 | Schizophrenia | Phase 3 | Completed | - | Japan ... More >> 69 Sites Tokyo, Etc, Japan Korea, Republic of 22 Sites Seoul, Etc, Korea, Republic of Malaysia 10 Sites Kuala Lumpur, Etc, Malaysia Taiwan 14Sites Taipei, Etc, Taiwan Less << |
NCT01614912 | - | Completed | - | - | |
NCT01192295 | - | Completed | - | - | |
NCT01081132 | Attention-Deficit/Hyperactivit... More >>y Disorder Less << | Phase 3 | Completed | - | - |
NCT01614899 | - | Completed | - | - | |
NCT01006356 | Cancer Pain | Phase 4 | Completed | - | - |
NCT01192295 | Pain | Phase 3 | Completed | - | - |
NCT01006356 | - | Completed | - | - | |
NCT01081132 | - | Completed | - | - | |
NCT00799487 | Attention Deficit Hyperactivit... More >>y Disorder Less << | Phase 4 | Completed | - | - |
NCT00799409 | Attention Deficit Hyperactivit... More >>y Disorder Less << | Phase 4 | Completed | - | United States, California ... More >> Irvine, California, United States United States, Texas Houston, Texas, United States Less << |
NCT00799409 | - | Completed | - | - | |
NCT01675167 | Low Back Pain | Phase 3 | Completed | - | - |
NCT01675167 | - | Completed | - | - | |
NCT00799487 | - | Completed | - | - | |
NCT01081145 | Attention-deficit/Hyperactivit... More >>y Disorder Less << | Phase 3 | Completed | - | - |
NCT01081145 | - | Completed | - | - | |
NCT01633944 | - | Completed | - | - | |
NCT02115906 | - | Unknown | May 2018 | Austria ... More >> Medical University Of Vienna, Department of Internal Medicine III Recruiting Vienna, Austria, 1090 Contact: Peter Wolf, MD 00431404004311 peter.wolf@meduniwien.ac.at Principal Investigator: Michael Krebs, MD, Prof Less << | |
NCT03500094 | Fabry Disease | Phase 3 | Recruiting | September 1, 2020 | United States, Florida ... More >> University of South Florida Recruiting Tampa, Florida, United States, 33606 United States, Georgia Emory University Division of Medical Genetics Recruiting Decatur, Georgia, United States, 30033 United States, Missouri University of Missouri Recruiting Columbia, Missouri, United States, 65201 United States, Ohio Cincinnati Children's Hospital Not yet recruiting Cincinnati, Ohio, United States, 45229 United States, Pennsylvania Children's Hospital of Philadelphia Not yet recruiting Philadelphia, Pennsylvania, United States, 19104 Children's Hospital of Pittsburgh of UPMC Recruiting Pittsburgh, Pennsylvania, United States, 15224 United States, Virginia Lysosomal & Rare Disorders Research & Treatment Center Recruiting Fairfax, Virginia, United States, 22030 Less << |
NCT01614899 | Schizophrenia | Phase 3 | Completed | - | Japan ... More >> 69 Sites Tokyo, Etc, Japan Korea, Republic of 22 Sites Seoul, Etc, Korea, Republic of Malaysia 10 Sites Kuala Lumpur, Etc, Malaysia Taiwan 14 Sites Taipei, Etc, Taiwan Less << |
NCT03393026 | Schizophrenia | Phase 4 | Recruiting | August 2019 | Taiwan ... More >> Taipei City Hospital, Songde Branch Recruiting Taipei, Taiwan Contact: Shih-Ku Lin, M.D. (02)2726-3141 Tri-Service General Hospital Recruiting Taipei, Taiwan Contact: Chin-Bin Yeh, M.D., Ph.D. 886-2-87923311 Less << |
NCT03560349 | Post-Dural Puncture Headache | Phase 2 | Enrolling by invitation | June 30, 2020 | United States, Utah ... More >> University of Utah Salt Lake City, Utah, United States, 84132 Less << |
NCT01633944 | Low Back Pain | Phase 3 | Completed | - | - |
NCT00322205 | Smoking Cessation | Phase 4 | Completed | - | United States, New York ... More >> State University of New York Buffalo, New York, United States Less << |
NCT01060150 | - | Completed | - | - | |
NCT01060150 | Attention Deficit Disorder Wit... More >>h Hyperactivity Less << | Phase 4 | Completed | - | - |
NCT03396250 | Pain | Phase 1 | Completed | - | United States, Texas ... More >> ICON Development Solutions, LLC San Antonio, Texas, United States, 78219 Less << |
NCT03424135 | Pain | Phase 1 | Completed | - | United States, Texas ... More >> ICON Development Solutions, LLC San Antonio, Texas, United States, 78219 Less << |
NCT01500694 | - | Completed | - | - | |
NCT01106430 | Attention-Deficit/Hyperactivit... More >>y Disorder Less << | Phase 3 | Completed | - | - |
NCT03539952 | Wilson Disease | Phase 3 | Recruiting | March 2021 | United States, Connecticut ... More >> Yale University School of Medicine Recruiting New Haven, Connecticut, United States, 06510 Contact: Ricarda Tomlin ricarda.tomlin@yale.edu Germany Innere Medizin Recruiting Heidelberg, Germany, 69120 Contact: Andrea Langel 49 6221-56 8388 andrea.langel@med.uni-heidelberg.de Contact: Jessica Langel jessica.langel@med.uni-heidelberg Poland Institute of Psychiatry and Neurology Recruiting Warsaw, Poland, 02 957 Contact: Beata Ziółkowska 48 2245 82 609 ziolko275@wp.pl Less << |
NCT00663117 | Inflammation ... More >>Crohn's Disease Less << | Phase 2 | Completed | - | United States, Pennsylvania ... More >> Penn State Hershey Medical Center Hershey, Pennsylvania, United States, 17033 Less << |
NCT01500694 | Attention Deficit Hyperactivit... More >>y Disorder (ADHD) Less << | Phase 3 | Completed | - | - |
NCT01106430 | - | Completed | - | - | |
NCT01322282 | Allergy | Phase 1 | Completed | - | Canada, Quebec ... More >> Algorithme Pharma Inc. Mount-Royal, Quebec, Canada, H3P 3P1 Less << |
NCT00663117 | - | Completed | - | - | |
NCT00005669 | Hyperinsulinemia ... More >> Obesity Less << | Phase 2 | Completed | - | United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less << |
NCT00715988 | Pain | Phase 1 | Completed | - | United States, Utah ... More >> University of Utah Salt Lake City, Utah, United States, 84108 Primary Children's Medical Center Salt Lake City, Utah, United States, 84113 Less << |
NCT00005669 | - | Completed | - | - | |
NCT00306735 | Multiple Myeloma | Phase 2 | Completed | - | United States, Indiana ... More >> Indiana Blood and Marrow Transplantation Beech Grove, Indiana, United States, 46107 United States, New York Cornell Medical Center New York, New York, United States, 10021 United States, North Carolina Wake Forest Medical Center Winston-Salem, North Carolina, United States, 27157 United States, Oregon Oregon Health & Science University Portland, Oregon, United States, 97239 United States, Pennsylvania University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Fox Chase-Temple Philadelphia, Pennsylvania, United States, 19111 United States, Texas Baylor University Blood and Marrow Transplantation Dallas, Texas, United States, 75246 MD Anderson Cancer Center Houston, Texas, United States, 77030 Texas Transplant Institute San Antonio, Texas, United States, 78229 United States, Virginia Fairfax-Northern Virginia Hematology-Oncology PC Fairfax, Virginia, United States, 22031 Less << |
NCT02015234 | - | Completed | - | - | |
NCT01863186 | Opioid Dependence ... More >> Acute Opioid Withdrawal Syndrome Less << | Phase 3 | Completed | - | United States, California ... More >> Clovis, California, United States, 93611 Escondido, California, United States, 92025 San Diego, California, United States United States, Florida Miami, Florida, United States, 33136 Orlando, Florida, United States, 32806 United States, Georgia Atlanta, Georgia, United States, 30308 United States, Illinois Oak Park, Illinois, United States, 60301 United States, Louisiana Lake Charles, Louisiana, United States, 70629 United States, Maryland Baltimore, Maryland, United States, 21229 United States, Mississippi Flowood, Mississippi, United States United States, Missouri Saint Louis, Missouri, United States United States, Ohio Dayton, Ohio, United States Mason, Ohio, United States, 45050 United States, Texas Austin, Texas, United States, 78731 Dallas, Texas, United States, 75208 DeSoto, Texas, United States, 75115 United States, Utah Orem, Utah, United States, 84058 Salt Lake City, Utah, United States, 84106 Less << |
NCT02015234 | Primary Fibromyalgia | Phase 3 | Completed | - | United States, Colorado ... More >> Denver Denver, Colorado, United States, 80239 United States, Florida 16176 Cortez Boulevard Brooksville, Florida, United States, 34601 100 West Gore Street Orlando, Florida, United States, 32806 United States, Maryland 71 Thomas Johnson Drive Frederick, Maryland, United States, 21702 United States, Massachusetts 370 Faunce Corner Road North Dartmouth, Massachusetts, United States, 02747 Worcester Worcester, Massachusetts, United States, 01605 United States, Mississippi Jackson Jackson, Mississippi, United States, 39202 United States, Ohio Cincinnati Cincinnati, Ohio, United States, 45219 1275 Olentangy River Road Columbus, Ohio, United States, 43212 18660 Bagley Road Middleburg Heights, Ohio, United States, 44130 United States, Pennsylvania 1001 South Market Street Mechanicsburg, Pennsylvania, United States, 17055 United States, South Carolina 322 Memorial Drive Greer, South Carolina, United States, 29650 United States, Washington 601 Broadway Seattle, Washington, United States, 98122 Less << |
NCT00790192 | Schizophrenia | Phase 3 | Completed | - | - |
NCT01466647 | Non Small Cell Lung Cancer | Phase 1 | Completed | - | Sweden ... More >> KFUE Uppsala, Sweden University Hospital Uppsala, Sweden Less << |
NCT00790192 | - | Completed | - | - | |
NCT01221740 | Back Pain | Phase 3 | Withdrawn(Company decided to d... More >>iscontinue) Less << | - | United States, Massachusetts ... More >> Brigham and Women's Hospital Pain Trials Center Chestnut Hill, Massachusetts, United States, 02467 Less << |
NCT00874120 | Blood Pressure ... More >> Human Experimentation Less << | Phase 3 | Completed | - | - |
NCT03465787 | Schizophrenia | Phase 3 | Recruiting | April 2019 | Korea, Republic of ... More >> Borame Medical Center Recruiting Seoul, Seoul, Dongjak-gu, Korea, Republic of, 07061 Contact: Jung Hee Yeon 82-2-870-2461 hyjung@snu.ac.kr Principal Investigator: Jung Hee Yeon, M.D. Less << |
NCT00615433 | Schizophrenia | Phase 3 | Completed | - | - |
NCT00615433 | - | Completed | - | - | |
NCT00549718 | - | Completed | - | - | |
NCT02597257 | Postherpetic Neuralgia ... More >> Diabetic Polyneuropathy Peripheral Neuropathy Less << | Phase 2 | Unknown | July 2016 | Korea, Republic of ... More >> Yong Chul Kim Recruiting Seoul, Korea, Republic of Contact: Yong Chul Kim, PhD +82-2-2072-3289 pain@snu.ac.kr Sub-Investigator: Jee Youn Moon, PhD Less << |
NCT00549718 | Schizophrenia | Phase 3 | Completed | - | - |
NCT00254878 | ADHD | Phase 3 | Completed | - | Germany ... More >> Novartis Investigational Site Freiburg, Germany Less << |
NCT00874120 | - | Completed | - | - |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
2.31mL 0.46mL 0.23mL |
11.54mL 2.31mL 1.15mL |
23.07mL 4.61mL 2.31mL |
|
Dissolving Methods |
in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day; The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound. Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:
|