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Chemical Structure| 861038-72-4 Chemical Structure| 861038-72-4

Structure of A2764 2HCl
CAS No.: 861038-72-4

Chemical Structure| 861038-72-4

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A2764 dihydrochloride is a selective inhibitor of TRESK (KCNK18) with an IC50 value of 11.8 μM. A2764 can inhibit TRESK in native cells, leading to cell depolarization and increased excitability.

Synonyms: A2764 (hydrochloride); A2764 dihydrochloride

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Product Details of A2764 2HCl

CAS No. :861038-72-4
Formula : C15H21Cl3N2O
M.W : 351.70
SMILES Code : ClC1=C2C=CC=NC2=C(OCCN(CC)CC)C=C1.[H]Cl.[H]Cl
Synonyms :
A2764 (hydrochloride); A2764 dihydrochloride
MDL No. :MFCD32667019
InChI Key :ZVRDPULCSHGKBD-UHFFFAOYSA-N
Pubchem ID :146013302

Safety of A2764 2HCl

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.84mL

0.57mL

0.28mL

14.22mL

2.84mL

1.42mL

28.43mL

5.69mL

2.84mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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