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Chemical Structure| 874374-25-1 Chemical Structure| 874374-25-1

Structure of Ned 19
CAS No.: 874374-25-1

Chemical Structure| 874374-25-1

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Ned 19 is a selective NAADP antagonist with membrane permeability that non-competitively inhibits NAADP-mediated Ca2+ signaling pathways, with an IC50 of 65 nM. Ned 19 significantly inhibits tumor growth, angiogenesis, and lung metastasis, showing broad potential applications in oncology.

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Product Details of Ned 19

CAS No. :874374-25-1
Formula : C30H31FN4O3
M.W : 514.59
SMILES Code : O=C(C1CC2=C(C(C3=CC=C(OC)C(CN4CCN(C5=CC=CC=C5F)CC4)=C3)N1)NC6=C2C=CC=C6)O
MDL No. :MFCD02057367
InChI Key :FUHCEERDBRGPQZ-UHFFFAOYSA-N
Pubchem ID :3978027

Safety of Ned 19

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.94mL

0.39mL

0.19mL

9.72mL

1.94mL

0.97mL

19.43mL

3.89mL

1.94mL

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