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Chemical Structure| 878155-45-4 Chemical Structure| 878155-45-4

Structure of 878155-45-4

Chemical Structure| 878155-45-4

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Product Details of [ 878155-45-4 ]

CAS No. :878155-45-4
Formula : C8H18N2O
M.W : 158.24
SMILES Code : NCCN1[C@H](COC)CCC1
English Name :(S)-2-(2-(Methoxymethyl)pyrrolidin-1-yl)ethanamine
MDL No. :MFCD21092820

Safety of [ 878155-45-4 ]

Application In Synthesis of [ 878155-45-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 878155-45-4 ]

[ 878155-45-4 ] Synthesis Path-Downstream   1~3

  • 2
  • [ 1426531-87-4 ]
  • [ 878155-45-4 ]
YieldReaction ConditionsOperation in experiment
With hydrogenchloride; water In methanol at 20℃; 2 Step 2: (S)-2-(2-(Methoxymethyl)pyrrolidin-1 -yl)ethanamine Step 2: (S)-2-(2-(Methoxymethyl)pyrrolidin-1 -yl)ethanamineA solution of (S)-tert-butyl 2-(2-(methoxymethyl)pyrrolidin-1-yl)ethylcarbamate (step 1 )(1 .89 g, 7.32 mmol) and in MeOH (5 ml) and treated with 2M HCI in MeOH (10 equivalents) at room temperature over the weekend. The solvent was removed in vacuo to afford the title compound;1 H NMR (400MHz, CDCI3) δ 3.45 (1 H, m), 3.25 (1 H, m), 3.1 (1 H, m), 2.9 (1 H, m), 2.8 (2H, m), 2.6 (1 H, m), 2.5 (3H, s), 2.4 (1 H, m), 2.2 (1 H, m), 0.8 (1 H, m), 1 .7 (2H, m), 1 .6 (1 H, m). T
  • 3
  • [ 63126-47-6 ]
  • [ 878155-45-4 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: potassium carbonate; triethylamine / acetonitrile / 85 °C 2: hydrogenchloride; water / methanol / 20 °C
 

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