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[ CAS No. 883230-68-0 ]

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2D
Chemical Structure| 883230-68-0
Chemical Structure| 883230-68-0
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Product Details of [ 883230-68-0 ]

CAS No. :883230-68-0MDL No. :MFCD08064043
Formula : C7H5BrN4 Boiling Point : -
Linear Structure Formula :-InChI Key :-
M.W :225.05Pubchem ID :-
Synonyms :

Computed Properties of [ 883230-68-0 ]

TPSA : - H-Bond Acceptor Count : -
XLogP3 : - H-Bond Donor Count : -
SP3 : - Rotatable Bond Count : -

Safety of [ 883230-68-0 ]

Signal Word:WarningClass:
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313UN#:
Hazard Statements:H315-H319Packing Group:
GHS Pictogram:

Application In Synthesis of [ 883230-68-0 ]

  • Upstream synthesis route of [ 883230-68-0 ]
  • Downstream synthetic route of [ 883230-68-0 ]

[ 883230-68-0 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 288-13-1 ]
  • [ 883230-68-0 ]
  • [ 883230-94-2 ]
YieldReaction ConditionsOperation in experiment
53% With caesium carbonate; copper(II) nitrate In N,N-dimethyl-formamide at 130℃; for 24 h; Schlenk technique General procedure: The 2-substituted 5-halopyridine or 5-halopyrimidine substrate (0.5 mmol), an N-heterocyclic amine (1.0 mmol), Cu(NO3)2 (0.1 mmol) and Cs2CO3 (1.0 mmol) were added to a 25-mL Schlenk tube, followed by addition of DMF (2 mL). This mixture was stirred at 130 °C or 140 °C (see schemes and tables) under air atmosphere for 24 h. Then, the reaction mixture was added to brine (15 mL) and this mixture was extracted with CH2Cl2 (3 × 15 mL). The combined extracts were concentrated under reduced pressure and the product was isolated by flash chromatography on a silica gel (200–300 mesh) column.
Reference: [1] Synthesis (Germany), 2017, vol. 49, # 23, p. 5120 - 5130
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[ 883230-68-0 ]

Imidazoles

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