Home Cart Sign in  
Chemical Structure| 88495-63-0 Chemical Structure| 88495-63-0
Chemical Structure| 88495-63-0

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69. It is a potential inhibitor of STAT-3 and EXP1 and exhibits selective cytotoxicity of cancer cells over normal cells in vitro.

Synonyms: Artesunic Acid; WR-256283; HSDB-7458

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of Artesunate

CAS No. :88495-63-0
Formula : C19H28O8
M.W : 384.42
SMILES Code : O=C(O)CCC(O[C@H]1O[C@@]2([H])[C@@]3(OO[C@](O2)(C)CC4)[C@]4([H])[C@H](C)CC[C@@]3([H])[C@H]1C)=O
Synonyms :
Artesunic Acid; WR-256283; HSDB-7458
MDL No. :MFCD00866204

Safety of Artesunate

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302+H312+H332
Precautionary Statements:P280

Application In Synthesis of Artesunate

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 88495-63-0 ]

[ 88495-63-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 29390-67-8 ]
  • [ 88495-63-0 ]
  • mono(6-artesunate-amino-6-deoxy)β-cyclodextrin [ No CAS ]
YieldReaction ConditionsOperation in experiment
57% A solutionof 0.5 g ATS (1.2 mmol), 0.4 g EDCI (2.0 mmol), and 0.3 g NHS(2.3 mmol) in DMF (20 mL) was stirred for 45 min in an ice bath,then 1.1 g 1N-bCD (1.0 mmol) was added to the reaction. Themixture was allowed to react for additional 2 h in an ice bathand subsequently for 15 h at room temperature. After the reactionwas completed, the solution was removed by a rotary evaporator,and followed by the addition of double-distilled water.The clear solution was collected by filtration, and then waspoured into acetone. The precipitate was collected and purifiedon a Sephadex LH-20 column with aqueous solution as eluent.The synthetic procedures for mono(6-artesunate-ethylenediamino-6-deoxy)-b-cyclodextrin (ATS-2NbetaCD), mono(6-artesunate-diethylenetriamino-6-deoxy)-b-cyclodextrin (ATS-3NbetaCD),and mono(6-artesunate-triethylenetetraamino-6-deoxy)-b-cyclodextrin(ATS-4NbetaCD) were similar to the ATS-1NbetaCD describedabove.
 

Historical Records

Categories