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[ CAS No. 886498-30-2 ]

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Chemical Structure| 886498-30-2
Chemical Structure| 886498-30-2
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Product Details of [ 886498-30-2 ]

CAS No. :886498-30-2 MDL No. :MFCD04115901
Formula : C8H6F2O3 Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W :188.13 g/mol Pubchem ID :604773
Synonyms :

Safety of [ 886498-30-2 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P280-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H332-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 886498-30-2 ]

  • Downstream synthetic route of [ 886498-30-2 ]

[ 886498-30-2 ] Synthesis Path-Downstream   1~2

  • 1
  • 2-[(3S)-4,4-difluoropiperidin-3-yl]oxy}quinoline dihydrochloride [ No CAS ]
  • [ 886498-30-2 ]
  • [ 76-05-1 ]
  • [ 1620651-05-9 ]
YieldReaction ConditionsOperation in experiment
A solution of EDC (6.82 mg, 0.036 mmol), HOAT (4.84 mg, 0.036 mmol), DIEA(0.026 mL, 0.148 mmol), <strong>[886498-30-2]2,6-difluoro-3-methoxybenzoic acid</strong> (7.25 mg, 0.039 mmol) was stirred in DMF (0.5 mL) for 0.5 h, followed by the addition of 2-[(3S)-4,4-difluoropiperidin-3- yl]oxy}quinoline dihydrochloride (10.0 mg, 0.030 mmol). The solution was stirred for 6 h at ambient temperature, then purified directly by HPLC using a reversed phase CI 8 column and eluting with a gradient of H20:CH3CN:CF3C02H - 90: 10:0.1 to 5:95:0.1. The desired fractions were concentrated to yield the title compound as the trifluoroacetate salt.MS: m/z = 435 (M + 1); HRMS: m/z = 435.1308 (M+l); calculated m/z = 435.1326 (M+l) for C22H19F4N203.
  • 2
  • [ 1073277-19-6 ]
  • [ 886498-30-2 ]
  • C17H16F2O [ No CAS ]
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