Home Cart 0 Sign in  

[ CAS No. 889659-70-5 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 889659-70-5
Chemical Structure| 889659-70-5
Structure of 889659-70-5 * Storage: {[proInfo.prStorage]}

Quality Control of [ 889659-70-5 ]

Related Doc. of [ 889659-70-5 ]

SDS
Alternatived Products of [ 889659-70-5 ]
Alternatived Products of [ 889659-70-5 ]

Product Details of [ 889659-70-5 ]

CAS No. :889659-70-5 MDL No. :MFCD12546605
Formula : C13H19BO3 Boiling Point : -
Linear Structure Formula :- InChI Key :N/A
M.W :234.10 g/mol Pubchem ID :-
Synonyms :

Safety of [ 889659-70-5 ]

Signal Word:Warning Class:
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501 UN#:
Hazard Statements:H302-H312-H332 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 889659-70-5 ]

  • Downstream synthetic route of [ 889659-70-5 ]

[ 889659-70-5 ] Synthesis Path-Downstream   1~6

  • 1
  • [ 889659-69-2 ]
  • [ 73183-34-3 ]
  • [ 889659-70-5 ]
YieldReaction ConditionsOperation in experiment
84% With methanesulfonic acid(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II); potassium acetate In 1,4-dioxane; toluene at 95℃; for 16h; Inert atmosphere;
68% With 1,1'-bis-(diphenylphosphino)ferrocene; potassium acetate In 1,4-dioxane at 80℃; for 3h; 3.B (B) Synthesis of Compound 33-c In a nitrogen atmosphere, 5.45 g of commercially available Compound 33-b, 1.3 g of dichlorobistriphenylphosphine palladium, 1.08 g of bisdiphenylphosphinoferrocene (dppf), 5.75 g of potassium acetate, 50 ml of dioxane, and 5.0 g of Compound 33-a were mixed, and the mixture was stirred at an outside temperature of 80 C. for 3 hours. A saturated aqueous ammonium chloride solution and ethyl acetate were added to the reaction liquid, for extraction by ethyl acetate. An organic layer was washed with a saturated saline solution, dried over magnesium sulfate, and concentrated, and purified by silica gel column chromatography, to thereby obtain 3.1 g (68% yield) of Compound 33-c. 1H NMR (300 MHz, CDCl3) ? (ppm): 1.34 (12H, s), 2.30 (3H, s), 4.88 (1H,s), 6.79 (1H,s), 7.08 (1H,s), 7.25 (1H,s)
  • 2
  • [ 889659-70-5 ]
  • [ 115753-34-9 ]
  • [ 889659-71-6 ]
YieldReaction ConditionsOperation in experiment
74% Stage #1: 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; 4-amino-5-bromophthalodinitrile With potassium carbonate; tris-(o-tolyl)phosphine In water; isopropyl alcohol; toluene at 80℃; for 3h; Stage #2: With hydrogenchloride In water; ethyl acetate; isopropyl alcohol; toluene 3.C (C) Synthesis of Compound 33-d In a nitrogen atmosphere, 3.1 g of Compound 33-c, 2.94 g of Compound 31-e, 3.65 g of potassium carbonate, 0.15 g of palladium acetate, 0.4 g of tri(o-tolyl)phosphine, 15 ml of toluene, 5 ml of water, and 10 ml of isopropyl alcohol were mixed, and the mixture was stirred at an outside temperature of 80 C. for 3 hours. 1M hydrochloric acid and ethyl acetate were added to the reaction liquid, for extraction by ethyl acetate. An organic layer was washed with a saturated saline solution, dried over magnesium sulfate, and concentrated, and purified by silica gel column chromatography, to thereby obtain 2.45 g (74% yield) of Compound 33-d.
  • 3
  • [ 504-15-4 ]
  • [ 889659-70-5 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: 2,6-dimethylpyridine; dmap / dichloromethane / 3 h / 0 - 20 °C 2: methanesulfonic acid(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II); potassium acetate / toluene; 1,4-dioxane / 16 h / 95 °C / Inert atmosphere
  • 4
  • [ 889659-70-5 ]
  • [ 75-03-6 ]
  • [ 1256346-05-0 ]
YieldReaction ConditionsOperation in experiment
0.11 g Stage #1: 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; ethyl iodide With potassium carbonate In N,N-dimethyl-formamide at 90℃; Stage #2: With sodium periodate In tetrahydrofuran; water for 0.25h; Stage #3: With hydrogenchloride In tetrahydrofuran; water at 20℃; for 4h;
  • 5
  • [ 889659-70-5 ]
  • [ 75-26-3 ]
  • (3-isopropoxy-5-methylphenyl)boronic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
0.178 g Stage #1: 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; isopropyl bromide With potassium carbonate In N,N-dimethyl-formamide at 90℃; Stage #2: With sodium periodate In tetrahydrofuran; water for 0.25h; Stage #3: With hydrogenchloride In tetrahydrofuran; water at 20℃; for 4h;
  • 6
  • [ 889659-70-5 ]
  • [ 100-39-0 ]
  • (3-(benzyloxy)-5-methylphenyl)boronic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
0.228 g Stage #1: 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; benzyl bromide With potassium carbonate In N,N-dimethyl-formamide at 90℃; Stage #2: With sodium periodate In tetrahydrofuran; water for 0.25h; Stage #3: With hydrogenchloride In tetrahydrofuran; water at 20℃; for 4h;
Historical Records

Related Functional Groups of
[ 889659-70-5 ]

Organoboron

Chemical Structure| 1398414-30-6

[ 1398414-30-6 ]

4-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

Similarity: 0.96

Chemical Structure| 517864-13-0

[ 517864-13-0 ]

5-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

Similarity: 0.95

Chemical Structure| 365564-09-6

[ 365564-09-6 ]

2-(3-Methoxy-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Similarity: 0.93

Chemical Structure| 2095797-27-4

[ 2095797-27-4 ]

2-Hydroxy-3-methylphenylboronic acid pinacol ester

Similarity: 0.92

Chemical Structure| 2095797-27-4

[ 2095797-27-4 ]

2-Hydroxy-3-methylphenylboronic acid pinacol ester

Similarity: 0.92

Aryls

Chemical Structure| 1398414-30-6

[ 1398414-30-6 ]

4-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

Similarity: 0.96

Chemical Structure| 517864-13-0

[ 517864-13-0 ]

5-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

Similarity: 0.95

Chemical Structure| 365564-09-6

[ 365564-09-6 ]

2-(3-Methoxy-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Similarity: 0.93

Chemical Structure| 331273-58-6

[ 331273-58-6 ]

2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

Similarity: 0.92

Chemical Structure| 269410-25-5

[ 269410-25-5 ]

2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

Similarity: 0.92

Organoboron

Chemical Structure| 1398414-30-6

[ 1398414-30-6 ]

4-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

Similarity: 0.96

Chemical Structure| 517864-13-0

[ 517864-13-0 ]

5-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

Similarity: 0.95

Chemical Structure| 365564-09-6

[ 365564-09-6 ]

2-(3-Methoxy-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Similarity: 0.93

Chemical Structure| 2095797-27-4

[ 2095797-27-4 ]

2-Hydroxy-3-methylphenylboronic acid pinacol ester

Similarity: 0.92

Chemical Structure| 2095797-27-4

[ 2095797-27-4 ]

2-Hydroxy-3-methylphenylboronic acid pinacol ester

Similarity: 0.92

Esters

Chemical Structure| 1398414-30-6

[ 1398414-30-6 ]

4-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

Similarity: 0.96

Chemical Structure| 517864-13-0

[ 517864-13-0 ]

5-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

Similarity: 0.95

Chemical Structure| 365564-09-6

[ 365564-09-6 ]

2-(3-Methoxy-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Similarity: 0.93

Chemical Structure| 1604802-47-2

[ 1604802-47-2 ]

3-Hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

Similarity: 0.92

Chemical Structure| 2095797-27-4

[ 2095797-27-4 ]

2-Hydroxy-3-methylphenylboronic acid pinacol ester

Similarity: 0.92