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Chemical Structure| 91678-81-8 Chemical Structure| 91678-81-8

Structure of 91678-81-8

Chemical Structure| 91678-81-8

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Product Details of [ 91678-81-8 ]

CAS No. :91678-81-8
Formula : C6H9N3
M.W : 123.16
SMILES Code : CC1=CN=C(N)C(C)=N1
MDL No. :MFCD00107172
InChI Key :GZZRWBRYYZGTNW-UHFFFAOYSA-N
Pubchem ID :2774764

Safety of [ 91678-81-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H317-H319
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 91678-81-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 91678-81-8 ]

[ 91678-81-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 38557-72-1 ]
  • [ 91678-81-8 ]
YieldReaction ConditionsOperation in experiment
84% With ammonium hydroxide; copper(II) oxide; at 150℃; for 72.0h;Sealed tube; Part 1, Step B: A mixture of <strong>[38557-72-1]2-chloro-3,5-dimethylpyrazine</strong> (28.5 g, 0.2 mol), prepared above, CuO (0.8 g, 0.01 mol) and concentrated aqueous NH3 (28-30 %, 150 mL) was stirred in a sealed pressure vessel at 150 C for 3 days. After cooling, the mixture was concentrated to dryness and the residue was treated with ethyl acetate (500 mL), then stirred for 15 minutes and filtered. The precipitate was washed with additional ethyl acetate (about 1.5 L) until the starting material was no longer detected in the filtrate. The filtrates were combined and concentrated. The residue was chromatographed on a silica gel column (MeOH/CH2Cl2, 0-10%) to furnish a yellow/brownish solid (20.7 g, 84%). 1H NMR (500 MHz, CHLOROFORM-^) delta ppm 7.68 (1H, s), 2.46 (3H, s), 2.42 (3H, d, J=0.63 Hz).
 

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Related Functional Groups of
[ 91678-81-8 ]

Amines

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Related Parent Nucleus of
[ 91678-81-8 ]

Pyrazines

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