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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 92285-87-5 Chemical Structure| 92285-87-5

Structure of L82-G17
CAS No.: 92285-87-5

Chemical Structure| 92285-87-5

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L82-G17 is a non-competitive selective inhibitor of DNA ligase I (Lig I) that blocks the third step of the ligation reaction (phosphodiester bond formation). This compound can serve as a tool for studying DNA repair mechanisms and catalytic activity probes.

4.5 *For Research Use Only !

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Product Details of L82-G17

CAS No. :92285-87-5
Formula : C11H9ClN4O2
M.W : 264.67
SMILES Code : OC1=CC(/C=N/NC(C=NN2)=C(Cl)C2=O)=CC=C1
MDL No. :N/A

Safety of L82-G17

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H318
Precautionary Statements:P264-P270-P280-P301+P312-P305+P351+P338-P310-P330-P501
Class:8
UN#:1759
Packing Group:

Related Pathways of L82-G17

DNA

Isoform Comparison

Biological Activity

Description
L82-G17 functions as an uncompetitive DNA ligase I (Lig I)-selective inhibitor, hindering phosphodiester bond formation, specifically in the third step of the ligation reaction. It can be utilized as a probe to assess catalytic activity[1].

Protocol

Bio Calculators
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1 mM

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10 mM

3.78mL

0.76mL

0.38mL

18.89mL

3.78mL

1.89mL

37.78mL

7.56mL

3.78mL

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