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Chemical Structure| 943-73-7 Chemical Structure| 943-73-7
Chemical Structure| 943-73-7

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H-HoPhe-OH is a hydroxyphenylalanine derivative frequently used in peptide synthesis.

Synonyms: L-Homophenylalanine

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Product Details of L-Homophenylalanine

CAS No. :943-73-7
Formula : C10H13NO2
M.W : 179.22
SMILES Code : O=C(O)[C@@H](N)CCC1=CC=CC=C1
Synonyms :
L-Homophenylalanine
MDL No. :MFCD00002619
InChI Key :JTTHKOPSMAVJFE-VIFPVBQESA-N
Pubchem ID :2724505

Safety of L-Homophenylalanine

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of L-Homophenylalanine

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 943-73-7 ]

[ 943-73-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 943-73-7 ]
  • [ 115-11-7 ]
  • [ 83079-77-0 ]
YieldReaction ConditionsOperation in experiment
With sulfuric acid; In 1,4-dioxane; at -78 - 20℃; for 72h; The solution of starting material is then cooled to -78 C. and the cold liquid isobutylene is added. The mixture is stirred at room temp in a pressure bottle for 3 days. The bottle is then cooled to -78 C. and opened. It is then stirred while open and allowed to warm up in an ice bath. After 20 minutes of stirring, 55 ml of 2N NaOH are added slowly at 0 C. The product is extracted with ether and washed with dilute sodium bicarbonate. The solution is dried over sodium sulfate and the solvent is removed to give 4.9 g of the t-butyl ester as a yellow oil.
 

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