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Chemical Structure| 949912-58-7 Chemical Structure| 949912-58-7

Structure of Remodelin
CAS No.: 949912-58-7

Chemical Structure| 949912-58-7

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Remodelin is a potent and selective inhibitor of the acetyl-transferase protein NAT10.

4.5 *For Research Use Only !

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Product Details of Remodelin

CAS No. :949912-58-7
Formula : C15H14N4S
M.W : 282.36
SMILES Code : N#CC1=CC=C(C2=CSC(NN=C3CCCC3)=N2)C=C1
MDL No. :MFCD28167837
InChI Key :XAEJIFARBQJLML-UHFFFAOYSA-N
Pubchem ID :44442376

Safety of Remodelin

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H318
Precautionary Statements:P264-P270-P280-P301+P312+P330-P305+P351+P338+P310-P501
Class:8
UN#:1759
Packing Group:

Related Pathways of Remodelin

epigenetics

Isoform Comparison

Biological Activity

Description
Remodelin is an orally active and selective inhibitor of acetyltransferase NAT10. Remodelin inhibits NAT10 activitity and slows DNA replication and suppresses growth of prostate cancer cells.Additionally, Remodelin curtails the development of prostate cancer and hepatocellular carcinoma in xenograft models and prolongs the lifespan in models of Hutchinson-Gilford Progeria Syndrome (HGPS)[1].[2].[3].[4].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.54mL

0.71mL

0.35mL

17.71mL

3.54mL

1.77mL

35.42mL

7.08mL

3.54mL

References

 

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