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Chemical Structure| 21414-41-5 Chemical Structure| 21414-41-5

Structure of Glucoraphanin
CAS No.: 21414-41-5

Chemical Structure| 21414-41-5

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Glucoraphanin, a natural product isolated and purified from the seeds of Raphanus sativus L., with antioxidant and chemoprevention activiy, and can ameliorates obesity and insulin resistance through adipose tissue browning and reduction of metabolic endotoxemia in mice.

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Product Details of Glucoraphanin

CAS No. :21414-41-5
Formula : C12H23NO10S3
M.W : 437.51
SMILES Code : OC[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)S/C(CCCCS(C)=O)=N\OS(=O)(O)=O)O)O)O
MDL No. :MFCD08460269

Safety of Glucoraphanin

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT03013465 Healthy Volunteers Not Applicable Completed - United States, Maryland ... More >> USDA-ARS, Beltsville Human Nutrition Research Center Beltsville, Maryland, United States, 20705 Less <<
NCT02821728 Prostate Cancer Not Applicable Completed - United Kingdom ... More >> Institute of Food Research Norwich, Norfolk, United Kingdom, NR4 7UA Less <<
NCT02656420 Environmental Carcinogenesis Phase 1 Phase 2 Completed - China, Jiangsu ... More >> Qidong Liver Cancer Institute Qidong, Jiangsu, China, 226200 Less <<
NCT01950143 Prostate Cancer Not Applicable Completed - United Kingdom ... More >> Norfolk and Norwich University Hospital Norwich, United Kingdom, NR4 7UY Less <<
NCT02654743 Autism Phase 2 Unknown May 2017 -
NCT02810964 Schizophrenia ... More >> Schizoaffective Disorder Less << Phase 2 Enrolling by invitation July 2019 United States, Maryland ... More >> Sheppart Pratt Health System Towson, Maryland, United States, 21204 Less <<
NCT03289832 Healthy Adults Not Applicable Recruiting December 1, 2018 United States, Maryland ... More >> Johns Hopkins Recruiting Baltimore, Maryland, United States, 21224 Contact: Cutaneous Translational Research Program (CTReP)    410-502-7546    ctrep@jhmi.edu Less <<
NCT02677051 Autism Autist... More >>ic Disorder Autism Spectrum Disorder Autistic Behavior Less << Phase 2 Recruiting January 2022 United States, New Jersey ... More >> Rutgers University - Staged Research Building Recruiting Piscataway, New Jersey, United States, 08854 Contact: Edward S Stenroos    732-235-5490    stenroos@rutgers.edu Less <<
NCT02404428 Prostate Cancer Not Applicable Terminated(Problems with recru... More >>itment) Less << - United Kingdom ... More >> Cambridge University Hospitals NHS Foundation Trust_Addenbrooke's Hospital Cambridge, United Kingdom, CB2 0QQ Less <<
NCT02023931 Healthy Subject Early Phase 1 Completed - United States, Pennsylvania ... More >> Eye and Ear Institute Pittsburgh, Pennsylvania, United States, 15213 UPMC Hillman Cancer Center (University of Pittsburgh Cancer Institute) Pittsburgh, Pennsylvania, United States, 15232 Less <<
NCT01114399 Cardiovascular Disease Not Applicable Completed - United Kingdom ... More >> Institute of Food Research Norwich, Norfolk, United Kingdom, NR4 7UA Less <<
NCT01437501 Environmental Carcinogenesis Phase 2 Completed - China, Jiangsu ... More >> Qidong Liver Cancer Institute Qidong, Jiangsu, China, 226200 Less <<
NCT00252018 Diabetes Mellitus ... More >> Hypertension Hypercholesterolemia Cardiovascular Disease Less << Not Applicable Completed - Denmark ... More >> Bispebjerg Hospital Copenhagen, Denmark, 2400 Less <<
NCT03399656 Healthy Volunteers Not Applicable Completed - China, Jiangsu ... More >> Qidong Liver Cancer Institute Qidong, Jiangsu, China, 226200 Less <<
NCT01879878 Pancreatic Ductal Adenocarcino... More >>ma Less << Not Applicable Unknown December 2015 Germany ... More >> Dept. of General and Transplant Surgery, University Hospital of Heidelberg, Germany Recruiting Heidelberg, Germany, 69120 Contact: Vladimir J. Lozanovski, M.D.    +49 6221 5636439    vladimir.lozanovski@med.uni-heidelberg.de    Sub-Investigator: Vladimir J. Lozanovski, M.D. Less <<
NCT02909959 Autism Spectrum Disorder ... More >> Autistic Disorder Neurodevelopmental Disorder Childhood Developmental Disorders, Pervasive Less << Phase 2 Recruiting November 2019 United States, North Carolina ... More >> Carolina Institute for Developmental Disabilities, University of North Carolina School of Medicine Recruiting Carrboro, North Carolina, United States, 27510 Contact: Laura Politte, M.D.    919-445-4160    laura.politte@cidd.unc.edu    Contact: Morgan Parlier, MSW    919-843-8122    morgan.parlier@cidd.unc.edu Less <<
NCT01437501 - Completed - -
NCT02300324 Healthy Not Applicable Completed - United Kingdom ... More >> Institute of Food Research Norwich, Norfolk, United Kingdom, NR4 7UY Less <<
NCT01008826 Healthy Phase 1 Completed - China, Jiangsu ... More >> Qidong Liver Cancer Institute Qidong, Jiangsu, China, 226200 Less <<
NCT01927666 Healthy Not Applicable Completed - United Kingdom ... More >> Institute Of Food Research Norwich, Norfolk, United Kingdom, NR4 7UA Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.29mL

0.46mL

0.23mL

11.43mL

2.29mL

1.14mL

22.86mL

4.57mL

2.29mL

Dissolving Methods
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

References

 

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