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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 349106-80-5 Chemical Structure| 349106-80-5

Structure of LDCA
CAS No.: 349106-80-5

Chemical Structure| 349106-80-5

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LDCA is a dual-action metabolic modulator that inhibits lactate dehydrogenase A (LDH-A) activity and promotes apoptosis in malignant cells, widely applied in cancer progression research.

4.5 *For Research Use Only !

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Product Details of LDCA

CAS No. :349106-80-5
Formula : C8H5Cl3FNO
M.W : 256.49
SMILES Code : O=C(NC1=CC=C(F)C(Cl)=C1)C(Cl)Cl

Safety of LDCA

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314
Precautionary Statements:P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P403+P233-P501
Class:8
UN#:3261
Packing Group:

Related Pathways of LDCA

GPCR

Isoform Comparison

Biological Activity

Description
LDCA acts as a dual-hit metabolic modulator, inhibiting LDH-A enzyme activity to promote apoptosis in cancer cells. It is used in cancer progression research[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.90mL

0.78mL

0.39mL

19.49mL

3.90mL

1.95mL

38.99mL

7.80mL

3.90mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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