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Chemical Structure| 592542-60-4 Chemical Structure| 592542-60-4

Structure of Rigosertib sodium
CAS No.: 592542-60-4

Chemical Structure| 592542-60-4

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Rigosertib sodium is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM.

Synonyms: ON-01910 sodium

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Product Details of Rigosertib sodium

CAS No. :592542-60-4
Formula : C21H24NNaO8S
M.W : 473.47
SMILES Code : O=C([O-])CNC1=CC(CS(=O)(/C=C/C2=C(OC)C=C(OC)C=C2OC)=O)=CC=C1OC.[Na+]
Synonyms :
ON-01910 sodium
MDL No. :MFCD11655911

Safety of Rigosertib sodium

Related Pathways of Rigosertib sodium

PI3K-AKT

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.11mL

0.42mL

0.21mL

10.56mL

2.11mL

1.06mL

21.12mL

4.22mL

2.11mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

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