Home Cart Sign in  
Chemical Structure| 2313525-20-9 Chemical Structure| 2313525-20-9

Structure of SET2
CAS No.: 2313525-20-9

Chemical Structure| 2313525-20-9

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

SET2 is a TRPV2 antagonist that effectively blocks TRPV2 channels and inhibits prostate cancer cell migration, making it suitable for cancer and calcium signaling pathway research.

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of SET2

CAS No. :2313525-20-9
Formula : C17H21F3N4O2S
M.W : 402.43
SMILES Code : O=C(NCC1=CC=CO1)CCSC2=NC(C(F)(F)F)=CC(N(C)CCC)=N2
InChI Key :LZHSWRWIMQRTOP-UHFFFAOYSA-N
Pubchem ID :155541857

Safety of SET2

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Biological Activity

Description
SET2 is a specific TRPV2 antagonist with an IC50 of 0.46 μM. It inhibits the TRP channel and attenuates the migration of prostate cancer cells. Additionally, SET2 diminishes the elevation of cytoplasmic calcium induced by lysophosphatidic acid (LPA), an activator of TRPV2[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.48mL

0.50mL

0.25mL

12.42mL

2.48mL

1.24mL

24.85mL

4.97mL

2.48mL

References

 

Historical Records

Categories