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Chemical Structure| 1422253-37-9 Chemical Structure| 1422253-37-9

Structure of C-82
CAS No.: 1422253-37-9

Chemical Structure| 1422253-37-9

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C-82 is a selective β-catenin/CBP inhibitor with high affinity for β-catenin/CBP, with an IC50 value of 0.8 μM. C-82 exhibits antitumor activity and can be used in research on colorectal cancer and other β-catenin-related cancers.

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Product Details of C-82

CAS No. :1422253-37-9
Formula : C33H34N6O4
M.W : 578.66
SMILES Code : O=C(N([C@]([C@H](C)N1CC2=C3N=CC=CC3=CC=C2)([H])N4[C@@H](CC5=CC=C(O)C=C5)C1=O)N(C)CC4=O)NCC6=CC=CC=C6
MDL No. :MFCD32664545
InChI Key :KLGHKOORFHZFGO-AZXNYEMZSA-N
Pubchem ID :73602848

Safety of C-82

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT02349009 Systemic Scleroderma Phase 1 Phase 2 Completed - United States, Illinois ... More >> Chicago, Illinois, United States United States, Massachusetts Boston, Massachusetts, United States United States, New York New York, New York, United States Less <<
NCT02432027 Psoriasis Phase 1 Phase 2 Completed - Germany ... More >> Schwerin, Germany Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.73mL

0.35mL

0.17mL

8.64mL

1.73mL

0.86mL

17.28mL

3.46mL

1.73mL

References

 

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