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Chemical Structure| 351994-94-0 Chemical Structure| 351994-94-0
Chemical Structure| 351994-94-0

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Emeramide is an antioxidant and heavy metal chelator that exhibits potential applications in cancer and neurodegenerative disease treatment by regulating the cell cycle, transcription factors, and antioxidant and anti-inflammatory mechanisms.

Synonyms: NBMI; BDTH2

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of Emeramide

CAS No. :351994-94-0
Formula : C12H16N2O2S2
M.W : 284.40
SMILES Code : O=C(NCCS)C1=CC=CC(C(NCCS)=O)=C1
Synonyms :
NBMI; BDTH2
English Name :N1,N3-Bis(2-mercaptoethyl)isophthalamide
MDL No. :MFCD28144550
InChI Key :JUTBAVRYDAKVGQ-UHFFFAOYSA-N
Pubchem ID :21133161

Safety of Emeramide

Application In Synthesis of Emeramide

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 351994-94-0 ]

[ 351994-94-0 ] Synthesis Path-Downstream   1~6

  • 1
  • [ 351994-94-0 ]
  • [ CAS Unavailable ]
  • [ 934468-78-7 ]
YieldReaction ConditionsOperation in experiment
65% In ethanol; water aq. soln. CdCl2 was added to soln. ligand in EtOH; ppt. was filtered and dried in vacuo; elem. anal.;
  • 2
  • [ 351994-94-0 ]
  • [ CAS Unavailable ]
  • [ 934468-82-3 ]
YieldReaction ConditionsOperation in experiment
93% In ethanol; water aq. soln. Pb(OAc)2*3H2O was added to soln. ligand in EtOH; ppt. was filtered and dried in vacuo; elem. anal.;
  • 3
  • [ 351994-94-0 ]
  • [ CAS Unavailable ]
  • [ 410089-35-9 ]
YieldReaction ConditionsOperation in experiment
100% In ethanol; water aq. soln. HgCl2 was added to soln. ligand in EtOH; ppt. was filtered and dried in vacuo; elem. anal.;
  • 4
  • [ 351994-94-0 ]
  • [ 1590421-48-9 ]
  • [ 1590421-51-4 ]
YieldReaction ConditionsOperation in experiment
With hydrogenchloride; sodium selenite In ethanol for 4h; Overall yield = 92.5%; Overall yield = 2.7g;
  • 5
  • [ 100-69-6 ]
  • [ 351994-94-0 ]
  • [ 2377321-18-9 ]
YieldReaction ConditionsOperation in experiment
2.6 g In isopropyl alcohol at 20℃; Reflux; 1.1.33 Example 1.33: N1,N3-bis[2-[2-(2-Pyridyl)ethylsulfanyl]ethyl]benzene-1,3-dicarboxamide To a suspension of 2 g emeramide in 20 ml iso-propanol was added 1 ,54 ml 2-vinylpyridine. After stirring 7,5 hours at reflux the reaction mixture was cooled to room temperature and stirred overnight. After concentration in vacuo the residue was purified by chromatography on silica gel with dichloromethane/methanol as the eluents (eluation with a gradient) to yield 2,6 g of N1 ,N3- bis[2-[2-(2-Pyridyl)ethylsulfanyl]ethyl]benzene-1 ,3-dicarboxamide as a light yellowish oil (assay by C-NMR >95%).
  • 6
  • [ 156-57-0 ]
  • [ 99-63-8 ]
  • [ 351994-94-0 ]
YieldReaction ConditionsOperation in experiment
With triethylamine In chloroform at 20℃; for 4h;
 

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