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Chemical Structure| 915303-09-2 Chemical Structure| 915303-09-2

Structure of Indotecan
CAS No.: 915303-09-2

Chemical Structure| 915303-09-2

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Indotecan is a potent topoisomerase 1(Top1) inhibitor with IC50 values of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively.

Synonyms: LMP-400; NSC-724998

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Product Details of Indotecan

CAS No. :915303-09-2
Formula : C26H26N2O7
M.W : 478.49
SMILES Code : O=C1N(CCCN2CCOCC2)C3=C(C(C4=C3C=C(OCO5)C5=C4)=O)C6=C1C=C(OC)C(OC)=C6
Synonyms :
LMP-400; NSC-724998
MDL No. :MFCD25977124

Safety of Indotecan

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H341
Precautionary Statements:P201-P202-P281-P308+P313-P405-P501

Related Pathways of Indotecan

DNA

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT01794104 Neoplasm Lymp... More >>homa Less << Phase 1 Completed - United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less <<
NCT01051635 Neoplasms Lym... More >>phoma Less << Phase 1 Completed - United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.09mL

0.42mL

0.21mL

10.45mL

2.09mL

1.04mL

20.90mL

4.18mL

2.09mL

 

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