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Chemical Structure| 146-68-9 Chemical Structure| 146-68-9
Chemical Structure| 146-68-9

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INT is used in various dehydrogenase colorimetric analysis as the electron acceptor.

Synonyms: Iodonitrotetrazolium chloride; p-Iodonitrotetrazolium Violet; NSC 27620

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of INT

CAS No. :146-68-9
Formula : C19H13ClIN5O2
M.W : 505.70
SMILES Code : O=[N+](C1=CC=C([N+]2=NC(C3=CC=CC=C3)=NN2C4=CC=C(I)C=C4)C=C1)[O-].[Cl-]
Synonyms :
Iodonitrotetrazolium chloride; p-Iodonitrotetrazolium Violet; NSC 27620
English Name :2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazol-3-ium chloride
MDL No. :MFCD00011961
InChI Key :JORABGDXCIBAFL-UHFFFAOYSA-M
Pubchem ID :64957

Safety of INT

Application In Synthesis of INT

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 146-68-9 ]

[ 146-68-9 ] Synthesis Path-Downstream   1~8

  • 1
  • [ 544-16-1 ]
  • [ CAS Unavailable ]
  • [ 146-68-9 ]
YieldReaction ConditionsOperation in experiment
With hydrogenchloride; ethanol
  • 2
  • [ 146-68-9 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
In water Microbiological reaction;
YieldReaction ConditionsOperation in experiment
1-(4-Jodphenyl)-5-(4-nitrophenyl)-3-phenylformazan (I), iso-Amylnitrit/HCl, EtOH;
...ings. 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium, monosodium salt 2-(4-iodophenyl)-3-(2,4-dinitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium, monosodium salt 2-(2-methoxy-4-nitrophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium, monosodium salt 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazolium chloride 3,3'-(1,1'-biphenyl-4,4'-diyl)-bis(2,5-diphenyl)-2H-tetrazolium chloride 3,3'-[3,3'-dimethoxy-(1,1'-biphenyl)-4,4'-diyl]-bis[2-(4-nitrophenyl)-5-phenyl-2H-trazolium chloride] 2,3-diphenyl-5-(4-chlorophenyl)tetrazolium chloride 2,5-diphenyl-3-(p-diphenyl)tetrazolium chloride 2,3-diphenyl-5-(p-diphenyl)tetrazolium chloride 2,5-diphenyl-3-(4-styrylphenyl)tetrazolium chloride 2,5-diphenyl-3-(m-tolyl)tetrazolium chloride ...
  • 4
  • [ CAS Unavailable ]
  • [ 3316-09-4 ]
  • [ 146-68-9 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
In water mixing of aq. solns. of Na2MoO4*2H2O, 4-nitrocatechol and 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazolium chloride in acidic medium (pH 2.8 - 4.0); pptn., filtration, washing with cold water, drying at 75-80°C;
  • 5
  • [ 146-68-9 ]
  • [ 7781-49-9 ]
YieldReaction ConditionsOperation in experiment
With Gerovital H3; xanthine oxidase; xanthin at 25℃; for 0.166667h; aq. phosphate buffer; Enzymatic reaction;
With potassium superoxide; C11H15CuNO5 In dimethyl sulfoxide borate buffer;
  • 6
  • [ CAS Unavailable ]
  • [ 3316-09-4 ]
  • [ 146-68-9 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
With sulfuric acid In water Procedure for Establishing the OptimumConditions General procedure: Aliquots of Fe(III) solution, 4NC solution(up to 1.6 mL), TZS solution (up to 2.5 mL) and buffersolution (3 mL; pH ranging from 3.5to 7.0) wereintroduced into 125-mL separatory funnels. Theresulting solutions were diluted with distilled waterto a total volume of 10 mL. Then 10 mL of organicsolvent were added and the funnels were shakenfor a fixed time (up to 5.0 min). A portion of eachorganic extract was transferred through a filter paperinto a cell and the absorbance was read against ablank.
  • 7
  • [ CAS Unavailable ]
  • [ 146-68-9 ]
  • [ 37422-56-3 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
In chloroform; water General Procedure General procedure: Aliquots of V(V) solution, TAO solution (up to 2.7mL), buffer solution (1-3 mL; pH ranging from 3.2 to 7.3) and TZS solution (up to 1.7 mL) were pipetted into 100 mL separatory funnels. The volumes were made up to 10 mL with distilled water. Then 10 mL of chloroform were added. The funnels were closed with stoppers and shaken for a fixed time (up to 6.0 min). After separation of the layers, portions of the chloroform extracts were transferred through filter papers into cells. The absorbance was read against simultaneously prepared blank sample (TAO-buffer-TZS) or chloroform.
  • 8
  • [ CAS Unavailable ]
  • [ 7659-29-2 ]
  • [ 146-68-9 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
With sulfuric acid In chloroform; water 2. 2. Procedure for Establishmentof the Optimum Conditions for ComplexFormation The required aliquots of the solutions of Mo(VI), INT and H2SO4 were introduced into 250 mL separatory funnels. The resulting solutions were diluted with distilled water to a total volume of 10 mL. A required aliquot of a chloroform solution of 3,5-DNC was added and then the organic phase was adjusted to a volume of 10 mL with chloroform. The funnels were shaken for a fixed time (up to 240s). A portion of the organic extract was filtered through afilter paper into a 1 cm cell and the absorbance was measured against a blank. The blank extraction was performed in the same manner in the absence of molybdenum.
 

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