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Chemical Structure| 68399-77-9 Chemical Structure| 68399-77-9
Chemical Structure| 68399-77-9

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MOPSO is a buffering agent that remains stable within the physiological pH range, commonly used in biochemical and cell culture buffer systems.

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of MOPSO

CAS No. :68399-77-9
Formula : C7H15NO5S
M.W : 225.26
SMILES Code : OC(CN1CCOCC1)CS(O)(=O)=O
English Name :2-Hydroxy-3-morpholinopropane-1-sulfonic acid
MDL No. :MFCD00009629
InChI Key :NUFBIAUZAMHTSP-UHFFFAOYSA-N
Pubchem ID :109333

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Application In Synthesis of MOPSO

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 68399-77-9 ]

[ 68399-77-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 110-91-8 ]
  • [ 126-83-0 ]
  • [ 68399-77-9 ]
YieldReaction ConditionsOperation in experiment
In water; EXAMPLE 6 3-(N-morpholino)-2-hydroxypropyl sulfonic acid A mixture of 174.24 gms (2 moles) of morpholine, 300 cc. of water and 196.5 gms (1 mole) of sodium-3-chloro-2-hydroxypropyl sulfonate is charged to a 1-liter, 2-neck flask equipped with stirrer and condenser. The suspension is stirred vigorously and refluxed for 3 hours. After cooling to about 25 C., the solution is passed through a column of Dowex 50 in order to remove sodium cations and form the free acid. The elude from the column, containing the product, is evaporated to a thick oil under vacuum. Upon diluting with alcohol, the product, in the form of a zwitterion, crystallizes readily. The product is filtered, washed with alcohol and dried. The yield is 160 gms of a white material melting at 280 C. with decomposition. Analysis of the product indicates a carbon content of 37.38%, a hydrogen content of 6.74%, and a nitrogen content of 6.24%. The calculated values are carbon, 37.3%; hydrogen, 6.7%; and nitrogen, 6.2%. The pKa of this product at 20 C. is 6.95.
 

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