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Chemical Structure| 352554-02-0 Chemical Structure| 352554-02-0

Structure of SIRT1-IN-1
CAS No.: 352554-02-0

Chemical Structure| 352554-02-0

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SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC50 of 0.205 μM. SIRT1-IN-1 inhibits SIRT2 with an IC50 of 11.5 μM[1]. SIRT1-IN-1, a indole, is a cytomegalovirus (CMV) inhibitors and has antiviral activity[2].

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Product Details of SIRT1-IN-1

CAS No. :352554-02-0
Formula : C14H16N2O
M.W : 228.29
SMILES Code : O=C(C1C(NC2=C3C=C(C)C=C2)=C3CCC1)N
MDL No. :MFCD00846511

Safety of SIRT1-IN-1

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H319
Precautionary Statements:P264-P270-P280-P301+P312+P330-P305+P351+P338-P337+P313-P501

Related Pathways of SIRT1-IN-1

epigenetics

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

4.38mL

0.88mL

0.44mL

21.90mL

4.38mL

2.19mL

43.80mL

8.76mL

4.38mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
 

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