Home Cart Sign in  
Chemical Structure| 332063-87-3 Chemical Structure| 332063-87-3

Structure of SW157765
CAS No.: 332063-87-3

Chemical Structure| 332063-87-3

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

SW157765 is a selective non-canonical glucose transporter GLUT8 (SLC2A8) inhibitor. KRAS/KEAP1 double-mutant NSCLC cells show selective sensitivity to SW157765 due to the dual regulation of metabolic and anabolic genes by KRAS and NRF2.

Synonyms: SW157765

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of SW157765

CAS No. :332063-87-3
Formula : C19H13N3O3
M.W : 331.32
SMILES Code : O=C(NC1=CC2=C(OC(C3=CC=NC=C3)=N2)C=C1)/C=C/C4=CC=CO4
Synonyms :
SW157765
MDL No. :MFCD01539854
InChI Key :QSSYRORXXFTVFI-GQCTYLIASA-N
Pubchem ID :782267

Safety of SW157765

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Biological Activity

Description
SW157765 selectively inhibits the non-canonical glucose transporter GLUT8 (SLC2A8). NSCLC cells harboring KRAS/KEAP1 double mutations are particularly vulnerable to SW157765, due to its impact on metabolic and xenobiotic gene regulatory programs modulated by both KRAS and NRF2 [1][2].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.02mL

0.60mL

0.30mL

15.09mL

3.02mL

1.51mL

30.18mL

6.04mL

3.02mL

References

 

Historical Records

Categories