Structure of Topiramate
CAS No.: 97240-79-4
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Topiramate is a selective GluK1 kainate receptors (GluR5) antagonist with IC50 value of 0.46 μM which can act as a positive allosteric modulator of GABAA receptor-mediated currents, inhibit Nav channels and L-type Ca2+ channels.
Synonyms: McN 4853; RWJ 17021; Topax
4.5
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CAS No. : | 97240-79-4 |
Formula : | C12H21NO8S |
M.W : | 339.36 |
SMILES Code : | CC1(O[C@H]([C@@H](CO[C@@]2(COS(=O)(N)=O)O3)O1)[C@@H]2OC3(C)C)C |
Synonyms : |
McN 4853; RWJ 17021; Topax
|
MDL No. : | MFCD00865320 |
InChI Key : | KJADKKWYZYXHBB-XBWDGYHZSA-N |
Pubchem ID : | 5284627 |
GHS Pictogram: |
![]() ![]() |
Signal Word: | Warning |
Hazard Statements: | H315-H319-H335-H351-H361 |
Precautionary Statements: | P261-P305+P351+P338 |
Target |
|
In Vitro:
Concentration | Treated Time | Description | References |
Mouse cortical layer II/III pyramidal neurons | 50 μmol/L | 10 minutes | To evaluate the effect of SAS on eIPSCs, results showed that SAS reversibly decreased eIPSC amplitude and prolonged the τslow decay kinetics | PMC6771750 |
C2C12 myotubes | 1 or 100 μM | 45 minutes | To assess the effect of topiramate on glucose uptake and insulin signaling. Results showed that topiramate did not affect basal or insulin-stimulated glucose uptake. | PMC3799603 |
In Vivo:
Administration | Dosage | Frequency | Description | References |
Mice | Wild-type and familial hemiplegic migraine type 1 knock-in mice | Orogastric gavage | 80 mg/kg/d | Once daily for 7 weeks | Chronic topiramate treatment reduced susceptibility to KCl- or electrical stimulation-induced spreading depressions as well as ischemic depolarizations, and improved tissue and neurological outcomes | PMC4276468 |
DBA/2 mice | High impulsivity mouse model | Oral | 12.5, 25, 50 mg/kg | Acute administration: single dose 60 min before testing; Chronic administration: twice daily for 27 days | Evaluate the effects of topiramate on impulsive behaviors. Acute administration reduced motor impulsivity, chronic administration reduced cognitive impulsivity. | PMC3448922 |
Mice | No specific model mentioned | Intraperitoneal injection | 0.3, 1, 3, 10, 30, 100 mg/kg | Twice daily for 5 days | Investigate the effect of topiramate on glutamine synthetase activity in mouse brain. Single doses had no effect, but repeated administration dose-dependently reduced enzyme activity. | PMC1565942 |
Rats | ISDN-induced acute and chronic migraine model | Intravenous injection | 30 mg/kg | Single injection | Topiramate reversed ISDN-induced chronic mechanical allodynia, with effects comparable to those of mambalgin-1 and amiloride | PMC6177611 |
C57Bl/6J mice | High-fat diet-induced insulin resistance model | Oral (mixed in high-fat diet) | 0.12% (w/w) | 6 weeks continuously | To assess the effect of topiramate on insulin sensitivity. Results showed that topiramate improved insulin sensitivity and increased glucose uptake in heart, skeletal muscle, and adipose tissue. | PMC3799603 |
C57BL/6J mice | Cisplatin or oxaliplatin-induced neuropathy model | Intraperitoneal injection | 50 mg/kg | Single dose, assessed 24 hours after neuropathy induction | To evaluate the analgesic effects of topiramate on cisplatin or oxaliplatin-induced neuropathy. Results showed that topiramate lacked significant anti-allodynic effects in both models. | PMC4165414 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT00598923 | Traumatic Brain Injury ... More >> Epilepsy Less << | Early Phase 1 | Terminated(End of funding and ... More >>low enrollment) Less << | - | - |
NCT00210574 | Epilepsy, Absence | Phase 2 | Completed | - | - |
NCT00231556 | Epilepsy Seiz... More >>ures Epilepsies, Partial Epilepsy, Generalized Epilepsy, Tonic-Clonic Less << | Phase 3 | Completed | - | - |
NCT00448825 | Alcohol Dependence ... More >> Cocaine Dependence Less << | Phase 3 | Unknown | June 2013 | United States, Virginia ... More >> University of Virginia Center for Addiction Research and Education Recruiting Charlottesville, Virginia, United States, 22911 Contact: Mindy Borszich 888-882-2345 mcb3x@virginia.edu Contact: Eva Jenkins-Mendoza (434)243-0562 emj9c@virginia.edu Principal Investigator: Bankole Johnson, DSc,MD,PhD Sub-Investigator: Nassima Ait-Daoud, MD University of Virginia Center for Addiction Research and Education Recruiting Richmond, Virginia, United States, 23294 Contact: Mindy Borszich 888-882-2345 mcb3x@virginia.edu Contact: Eva Jenkins-Mendoza (434)243-0562 emj9c@virginia.edu Principal Investigator: Bankole Johnson, DSc,MD,PhD Sub-Investigator: Nassima Ait-Daoud, MD Less << |
NCT03176953 | PTSD and Alcohol Use Disorder | Phase 2 Phase 3 | Recruiting | October 31, 2021 | United States, California ... More >> VA San Diego Healthcare System, San Diego, CA Recruiting San Diego, California, United States, 92161 Contact: Sonya B Norman, PhD 858-552-8585 ext 5198 Sonya.Norman@va.gov Principal Investigator: Sonya B. Norman, PhD Less << |
NCT00153699 | Glaucoma, Angle-Closure | PHASE4 | UNKNOWN | 2025-07-07 | Hong Kong Eye Hospital, Kowloo... More >>n, Hong Kong|Prince of Wales Hospital, Shatin, Hong Kong Less << |
NCT00249691 | Cocaine-Related Disorders | Phase 3 | Unknown | October 2012 | United States, Virginia ... More >> UVA CARE Charlottesville, Virginia, United States, 22911 UVA CARE Richmond Richmond, Virginia, United States, 23294 Less << |
NCT00182520 | Obsessive Compulsive Disorder | Phase 4 | Recruiting | April 2019 | Canada, Ontario ... More >> MacAnxiety Research Centre Recruiting Hamilton, Ontario, Canada, L8S 1B7 Contact: Beth Patterson, BScN, BEd 905-921-7644 bpatter@mcmaster.ca Sub-Investigator: Catherine Mancini, MD, FRCPC Sub-Investigator: Steve Collins, MB, FRCPC Sub-Investigator: Jonathan Oakman, PhD Principal Investigator: Michael Van Ameringen, MD, FRCPC Less << |
NCT00725920 | Posttraumatic Stress Disorder | Phase 4 | Completed | - | Brazil ... More >> Federal University of Sao Paulo Sao Paulo, Brazil, 04023-061 Less << |
NCT01182766 | Alcohol Dependence ... More >> Nicotine Dependence Less << | Phase 2 Phase 3 | Recruiting | December 2017 | United States, California ... More >> University of California, San Diego Active, not recruiting La Jolla, California, United States, 92093 United States, Texas University of Texas MD Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 Contact: O'Neak Henigan 713-745-4472 OCHenigan@manderson.org Principal Investigator: Paul M Cinciripini, Ph.D. United States, Virginia University of Virginia Center for Addiction Research & Education Active, not recruiting Charlottesville, Virginia, United States, 22911 University of Virginia Center for Addiction Research & Education Active, not recruiting Richmond, Virginia, United States, 23294 Less << |
NCT00211744 | Obsessive-compulsive Disorder | Phase 4 | Completed | - | United States, New York ... More >> Mount Sinai School of Medicine New York, New York, United States, 10029 Less << |
NCT00725920 | - | Completed | - | - | |
NCT00182455 | Social Phobia | Phase 4 | Recruiting | March 2019 | Canada, Ontario ... More >> MacAnxiety Research Centre Recruiting Hamilton, Ontario, Canada, L8S 1B7 Contact: Beth Patterson, BScN, BEd 905-921-7644 bpatter@mcmaster.ca Principal Investigator: Michael Van Ameringen, MD, FRCPC Sub-Investigator: Steve Collins, MBChB, FRCPC Less << |
NCT00794313 | Parkinson's Disease | Not Applicable | Terminated(Funding Ended) | - | United States, Oregon ... More >> Oregon Health & Science University Portland, Oregon, United States, 97239 Less << |
NCT00370188 | Gambling | PHASE2 | WITHDRAWN | - | Centre for Addiction and Menta... More >>l Health, Toronto, Ontario, M5S 2S1, Canada Less << |
NCT00794313 | - | Terminated(Funding Ended) | - | - | |
NCT00421603 | - | Completed | - | - | |
NCT00297349 | Seizures|Epilepsy | COMPLETED | 2025-06-05 | - | |
NCT00233012 | Seizures | PHASE1 | COMPLETED | 2025-10-07 | - |
NCT00421603 | Cocaine Dependence | Phase 2 | Completed | - | United States, New York ... More >> STARS New York, New York, United States, 10032 Less << |
NCT00463775 | Alcohol Dependence|Borderline ... More >>Personality Disorder Less << | PHASE3 | WITHDRAWN | 2025-05-09 | - |
NCT00216567 | Epilepsy, Rolandic | Phase 4 | Completed | - | - |
NCT01843699 | Pathological Gambling | Phase 2 | Completed | - | Brazil ... More >> Instituto de Psiquiatria da Universidade de São Paulo São Paulo, Brazil, 05403-010 Less << |
NCT00905164 | - | Completed | - | - | |
NCT00266604 | Epilepsy|Seizures|Epilepsies, ... More >>Partial|Epilepsy, Generalized|Seizures, Tonic-Clonic Less << | PHASE4 | COMPLETED | 2025-06-07 | - |
NCT00905164 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... More >> Anapharm Inc. Sainte-Foy, Quebec, Canada, G1V 2K8 Less << |
NCT01749215 | Alcohol Dependence ... More >> Posttraumatic Stress Disorder (PTSD) Less << | Phase 4 | Recruiting | December 2018 | United States, California ... More >> San Francisco VA Medical Center Recruiting San Francisco, California, United States, 94121 Principal Investigator: Steven L. Batki, MD Less << |
NCT00231673 | Diabetic Neuropathies|Diabetes... More >> Mellitus, Type 2|Polyneuropathies Less << | PHASE2 | COMPLETED | 2025-01-03 | - |
NCT00685178 | - | Completed | - | - | |
NCT00956696 | - | Unknown | June 2013 | Hong Kong ... More >> Prince of Wales Hospital Recruiting Hong Kong, Hong Kong Less << | |
NCT00939705 | - | Completed | - | - | |
NCT00939705 | Healthy | Phase 1 | Completed | - | United States, Missouri ... More >> Gateway Medical Research, Inc. St, Charles, Missouri, United States Less << |
NCT01836874 | - | Completed | - | - | |
NCT00755716 | Tobacco Dependence | Phase 3 | Completed | - | United States, Connecticut ... More >> University of Connecticut Halth Center Farmington, Connecticut, United States, 06030 Less << |
NCT00755716 | - | Completed | - | - | |
NCT02098941 | - | Unknown | December 2014 | Korea, Republic of ... More >> Seoul National University Hospital Recruiting Seoul, Korea, Republic of Contact: Sang kun Lee, MD,PhD sangkun2923@gmail.com Contact: Jung-won Shin, MD limitsum@gmail.com Principal Investigator: Sang kun Lee, MD, PhD Less << | |
NCT00986128 | Bipolar Disorder | Phase 1 | Completed | - | - |
NCT00685178 | Cocaine Dependence | Phase 2 | Completed | - | United States, Maryland ... More >> Behavioral Pharmacology Research Unit Baltimore, Maryland, United States, 21224 Less << |
NCT03712917 | Migraine | Not Applicable | Completed | - | Turkey ... More >> Ataturk University Resarch Hospital Erzurum, Turkey, 25000 Less << |
NCT03280342 | Migraine Head... More >>ache Less << | Phase 2 | Terminated(Sponsor terminated ... More >>study) Less << | - | United States, Minnesota ... More >> University of Minnesota Minneapolis, Minnesota, United States, 55455 Prism Research Saint Paul, Minnesota, United States, 55114 Less << |
NCT00297336 | Migraine Disorders | COMPLETED | 2025-02-07 | - | |
NCT00216606 | Migraine | Phase 3 | Completed | - | - |
NCT02371889 | Alcoholism | Phase 2 | Recruiting | January 2021 | United States, Pennsylvania ... More >> Corporal Michael J. Crescenz VA Medical Center Recruiting Philadelphia, Pennsylvania, United States, 19104 Contact: Timothy S Pond, MPH 215-746-1959 timpond@pennmedicine.upenn.edu Principal Investigator: Henry Kranzler, MD University of Pennsylvania Treatment Research Center Recruiting Philadelphia, Pennsylvania, United States, 19104 Contact: Timothy S. Pond, M.P.H. 215-746-1959 timpond@pennmedicine.upenn.edu Principal Investigator: Henry R. Kranzler, M.D. Less << |
NCT00345371 | Methamphetamine | Phase 2 | Completed | - | United States, California ... More >> Matrix Institute on Addictions Costa Mesa, California, United States, 92627 South Bay Treatment Center San Diego, California, United States, 92105 Torrance Site Torrance, California, United States, 90502 United States, Hawaii John A. Burns School of Medicine Honolulu, Hawaii, United States, 96813 United States, Iowa Powell Chemical Dependency Center Des Moines, Iowa, United States, 50316 United States, Missouri University of Missouri - Kansas City Kansas City, Missouri, United States, 64108 United States, Utah Salt Lake City VA Medical Center Salt Lake City, Utah, United States, 84148 United States, Virginia UVA CARE Charlottesville, Virginia, United States, 22911 Less << |
NCT00345371 | - | Completed | - | - | |
NCT00753493 | Epilepsy Migr... More >>aines Less << | Phase 1 | Completed | - | United States, Minnesota ... More >> University of Minnesota Minneapolis, Minnesota, United States, 55455 Less << |
NCT01970566 | Obesity Diabe... More >>tes Mellitus Less << | Not Applicable | Withdrawn(The project was not ... More >>announced to the field and it was not funded.) Less << | November 2017 | United States, Illinois ... More >> Captain James A. Lovell Federal Health Care Center, North Chicago, IL North Chicago, Illinois, United States, 60064 Less << |
NCT01700387 | Chronic Migraine | Phase 4 | Completed | - | United States, Missouri ... More >> Clinvest/A Division of Banyan Group, Inc. Springfield, Missouri, United States, 65807 Less << |
NCT01060111 | Migraine | Phase 4 | Completed | - | Korea, Republic of ... More >> Busan, Korea, Republic of Daegu, Korea, Republic of Kwangjoo, Korea, Republic of Kyunggi-Do, Korea, Republic of Seoul, Korea, Republic of Uijeongbu, Korea, Republic of Less << |
NCT01060111 | - | Completed | - | - | |
NCT00216619 | Migraine | Phase 3 | Completed | - | - |
NCT01241019 | Hypoxic Ischemic Encephalopath... More >>y Less << | Phase 2 | Completed | - | Italy ... More >> Neonatal Intensive Care Unit - Azienda Ospedaliero-Universitaria Meyer Florence, Italy, I-50139 Neonatal Intensive Care Unit - Azienda Ospedaliero-Universitaria Pisana Pisa, Italy, I-56100 Less << |
NCT00732108 | Migraine Head... More >>ache Dizziness Less << | Not Applicable | Withdrawn(No subjects enrolled... More >>) Less << | - | United States, California ... More >> University of California, San Francisco San Francisco, California, United States, 94143 Less << |
NCT00223626 | Cocaine-Related Disorders | PHASE2 | COMPLETED | 2025-12-10 | University of Virginia CARE Ce... More >>nter for Addiction Research & Education, Charlottesville, Virginia, 22911, United States|UVA CARE Richmond, Richmond, Virginia, 23294, United States Less << |
NCT01700387 | - | Completed | - | - | |
NCT00167245 | Alcoholism Co... More >>caine Dependence Less << | Phase 2 | Completed | - | United States, Pennsylvania ... More >> University of Pennsylvania, Treatment Research Center Philadelphia, Pennsylvania, United States, 19104 Less << |
NCT00939692 | Healthy | PHASE1 | COMPLETED | 2025-04-07 | Gateway Medical Research, Inc.... More >>, St, Charles, Missouri, 63301, United States Less << |
NCT00167245 | - | Completed | - | - | |
NCT00988481 | Bulimia Nervosa | PHASE4 | WITHDRAWN | 2025-09-10 | Neuropsychiatric Research Inst... More >>itute (NRI), Fargo, North Dakota, 58103, United States Less << |
NCT00939692 | Healthy | PHASE1 | COMPLETED | 2025-04-07 | Gateway Medical Research, Inc.... More >>, St, Charles, Missouri, 63301, United States Less << |
NCT01384279 | Obesity | Not Applicable | Completed | - | Taiwan ... More >> Beitou Armed Forces Hospital Taipei, Taiwan, 11243 Less << |
NCT01834404 | Obesity | Phase 4 | Completed | - | United States, Minnesota ... More >> Mayo Clinic in Rochester Rochester, Minnesota, United States, 55905 Less << |
NCT00986336 | Bipolar Disorder | Phase 1 | Completed | - | - |
NCT00550394 | - | Completed | - | - | |
NCT00550394 | Bipolar Disorder ... More >> Alcohol Abuse Less << | Phase 4 | Completed | - | United States, Ohio ... More >> University of Cincinnati Medical Center Cincinnati, Ohio, United States, 45227 Less << |
NCT01627860 | Epilepsy | Phase 4 | Completed | - | - |
NCT01627860 | - | Completed | - | - | |
NCT01191086 | - | Completed | - | - | |
NCT01191086 | Epilepsy | Phase 3 | Completed | - | - |
NCT01834404 | - | Completed | - | - | |
NCT03479086 | Alcohol Dependence | Phase 3 | Recruiting | November 1, 2020 | Australia, New South Wales ... More >> Drug Health Services, Royal Prince Alfred Hospital Recruiting Sydney, New South Wales, Australia, 2050 Contact: Kirsten C Morley, PhD +61295153636 kirsten.morley@sydney.edu.au Contact: Central Intake 95157611 sydneyalcoholtreatmentgroup@gmail.com Principal Investigator: Paul Haber, MBBS Less << |
NCT01081795 | Migraine | Phase 2 | Completed | - | Japan ... More >> Bunkyo, Japan Chitose, Japan Hachioji, Japan Iruma, Japan Isehara, Japan Iwate, Japan Kagoshima, Japan Kamogawa, Japan Kitakyushu, Japan Kobe, Japan Kumamoto, Japan Kyoto, Japan Minato, Japan Morioka, Japan Nagoya, Japan Nishinomiya, Japan Sagamihara, Japan Sapporo, Japan Shimotsuga, Japan Shinjuku-Ku, Japan Shinjuku, Japan Shizuoka, Japan Suginami-Ku, Japan Tokyo, Japan Toyama, Japan Toyonaka, Japan Ube N/A, Japan Ube, Japan Yokohama, Japan Yonago N/A, Japan Less << |
NCT01081795 | - | Completed | - | - | |
NCT00203463 | PTSD | Phase 4 | Completed | - | United States, Alabama ... More >> Tuscaloosa Research & Education Advancement Corporation Tuscaloosa, Alabama, United States, 35404 Less << |
NCT00572117 | Bipolar Disorder|Alcoholism|Al... More >>cohol Dependence Less << | PHASE4 | COMPLETED | 2025-07-14 | Stanford/VA Palo Alto Mood Dis... More >>order Research Program, Palo Alto, California, 94304, United States Less << |
NCT00572117 | Bipolar Disorder|Alcoholism|Al... More >>cohol Dependence Less << | PHASE4 | COMPLETED | 2025-07-14 | Stanford/VA Palo Alto Mood Dis... More >>order Research Program, Palo Alto, California, 94304, United States Less << |
NCT00802412 | Nicotine Dependence ... More >> Alcohol Dependence Less << | Phase 2 | Completed | - | United States, California ... More >> VA San Diego Healthcare System, San Diego, CA San Diego, California, United States, 92161 Less << |
NCT02201251 | Epilepsy | Phase 3 | Recruiting | November 30, 2021 | - |
NCT00802412 | - | Completed | - | - | |
NCT02239913 | Cocaine Use Disorder | Phase 1 | Recruiting | June 2019 | United States, Kentucky ... More >> University of Kentucky Medical Center Recruiting Lexington, Kentucky, United States, 40536 Contact: William W Stoops, Ph.D. 859-257-5388 william.stoops@uky.edu Principal Investigator: Craig R Rush, Ph.D. Less << |
NCT03335163 | Migraine|Migraine;Menstrual|Co... More >>ntraception Less << | PHASE1 | COMPLETED | 2021-04-22 | University of Colorado Denver,... More >> Aurora, Colorado, 80045, United States Less << |
NCT02273804 | Obese Children and Adolescents | Phase 3 | Completed | - | France ... More >> Hopital Bicêtre Le Kremlin-Bicêtre, Paris, France, 94275 Less << |
NCT03308669 | Healthy | Phase 1 | Completed | - | United States, Wisconsin ... More >> Covance Madison CRU Madison, Wisconsin, United States, 53704 Less << |
NCT01229735 | Epilepsy | Phase 4 | Completed | - | Korea, Republic of ... More >> 14 Busan, Korea, Republic of 21 Busan, Korea, Republic of 8 Busan, Korea, Republic of 9 Busan, Korea, Republic of 12 Daegu, Korea, Republic of 13 Daegu, Korea, Republic of 10 Daejeon, Korea, Republic of 25 Daejeon, Korea, Republic of 15 Gwangju, Korea, Republic of 7 Incheon, Korea, Republic of 11 Kyunggi-Do, Korea, Republic of 19 Kyunggi-do, Korea, Republic of 23 Kyunggi-Do, Korea, Republic of 24 Kyunggi-Do, Korea, Republic of 16 Seoul, Korea, Republic of 17 Seoul, Korea, Republic of 18 Seoul, Korea, Republic of 1 Seoul, Korea, Republic of 2 Seoul, Korea, Republic of 3 Seoul, Korea, Republic of 4 Seoul, Korea, Republic of 5 Seoul, Korea, Republic of 6 Seoul, Korea, Republic of 22 Ulsan, Korea, Republic of Less << |
NCT00206336 | - | Completed | - | - | |
NCT01087736 | PTSD Alcohol ... More >>Abuse Alcoholism Less << | Phase 4 | Completed | - | United States, California ... More >> San Francisco VA Medical Center San Francisco, California, United States, 94121 Less << |
NCT01087736 | - | Completed | - | - | |
NCT00206336 | Tourette Syndrome | Phase 3 | Completed | - | - |
NCT00626925 | Alcohol Drinking | Phase 4 | Completed | - | United States, Pennsylvania ... More >> University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Less << |
NCT00626925 | - | Completed | - | - | |
NCT02191579 | Migraine Disorders | Phase 4 | Completed | - | - |
NCT00902473 | Healthy | COMPLETED | 2025-10-01 | MDS Pharina Services (Clinical... More >> Research Center), Quebec, H4R 2N6, Canada Less << | |
NCT01229735 | - | Completed | - | - | |
NCT02191579 | - | Completed | - | - | |
NCT00394095 | Bipolar Disorder ... More >> Weight Gain Less << | Phase 4 | Completed | - | United States, Ohio ... More >> University of Cincinnati Medical Center Cincinnati, Ohio, United States, 45267-0559 Less << |
NCT01764685 | - | Terminated(We terminated the s... More >>tudy due to problems recruiting alcoholic subjects with HIV.) Less << | - | - | |
NCT01110434 | Cannabis Abuse ... More >> Cannabis Dependence Less << | Phase 2 | Completed | - | United States, Rhode Island ... More >> Brown University, Center for Alcohol and Addiction Studies Providence, Rhode Island, United States, 02912 Less << |
NCT00901784 | Healthy | COMPLETED | 2025-10-01 | MDS Pharina Services (Clinical... More >> Research Center), St. Laurent, Québec, H4R 2N6, Canada Less << | |
NCT00300742 | Alcohol Dependence|Binge Eatin... More >>g Less << | PHASE2 | COMPLETED | 2025-07-08 | UVA CARE, Charlottesville, Vir... More >>ginia, 22911, United States|UVA CARE Richmond, Richmond, Virginia, 23294, United States Less << |
NCT01764685 | Heavy Drinking ... More >> HIV Alcohol Dependence Less << | Phase 2 | Terminated(We terminated the s... More >>tudy due to problems recruiting alcoholic subjects with HIV.) Less << | - | United States, Pennsylvania ... More >> University of Pennsylvania Treatment Research Center Philadelphia, Pennsylvania, United States, 19104 Less << |
NCT01689649 | Epilepsy | PHASE4 | COMPLETED | 2010-01-19 | Hanoi, Vietnam|Hochiminh, Viet... More >>nam Less << |
NCT01789047 | Idiopathic Parkinson's Disease... More >> Drug Induced Dyskinesia Less << | Phase 2 | Terminated(Sponsor withdrew su... More >>pport) Less << | - | United States, Alabama ... More >> University of Alabama Birmingham, Alabama, United States, 35233 United States, Florida University of South Florida Tampa, Florida, United States, 33612 United States, Illinois Rush University Medical Center Chicago, Illinois, United States, 60612 United States, North Carolina Duke University Durham, North Carolina, United States, 27705 United States, Oregon Oregon Health Sciences University Portland, Oregon, United States, 97201 Less << |
NCT00394095 | - | Completed | - | - | |
NCT02113787 | Epilepsy | Phase 4 | Completed | - | Korea, Republic of ... More >> Seoul National University Hospital Seoul, Korea, Republic of Less << |
NCT03767062 | Medication Overuse Headache ... More >> Chronic Migraine, Headache Less << | Not Applicable | Completed | - | Turkey ... More >> Mustafa Ceylan Erzurum, Turkey, 25000 Less << |
NCT01689649 | Epilepsy | PHASE4 | COMPLETED | 2010-01-19 | Hanoi, Vietnam|Hochiminh, Viet... More >>nam Less << |
NCT02639598 | Chronic Migraine | Phase 4 | Completed | - | - |
NCT01859013 | - | Completed | - | - | |
NCT02074904 | - | Terminated(We terminated the s... More >>tudy to run it as a sub-study of NCT02371889, which is a 13 week, placebo controlled, double-blind, trial of topiramate in heavy drinkers.) Less << | - | - | |
NCT00300742 | Alcohol Dependence|Binge Eatin... More >>g Less << | PHASE2 | COMPLETED | 2025-07-08 | UVA CARE, Charlottesville, Vir... More >>ginia, 22911, United States|UVA CARE Richmond, Richmond, Virginia, 23294, United States Less << |
NCT01765218 | Hypoxic Ischemic Encephalopath... More >>y Less << | Phase 1 Phase 2 | Recruiting | May 2020 | United States, California ... More >> UC Davis Medical Center Recruiting Sacramento, California, United States, 95822 Contact: Kristin R Hoffman, MD 916-734-3261 krhoffman@ucdavis.edu Contact: Catherine Rottkamp, MD carottkamp@ucdavis.edu Principal Investigator: Kristin R Hoffman, MD Sub-Investigator: Catherine Rottkamp, MD, PhD Sub-Investigator: Sameeia Iqbal, MD Less << |
NCT02074904 | Alcohol Drinking | Phase 2 | Terminated(We terminated the s... More >>tudy to run it as a sub-study of NCT02371889, which is a 13 week, placebo controlled, double-blind, trial of topiramate in heavy drinkers.) Less << | - | United States, Pennsylvania ... More >> University of Pennsylvania Center for Studies of Addiction Philadelphia, Pennsylvania, United States, 19104 Less << |
NCT00606411 | Sleep-Related Eating Disorder | Early Phase 1 | Recruiting | - | United States, Massachusetts ... More >> Massachusetts General Hospital Recruiting Boston, Massachusetts, United States, 02114 Less << |
NCT01859013 | Obesity, Morbid ... More >> Obesity Weight Loss Less << | Phase 2 | Completed | - | United States, Minnesota ... More >> University of Minnesota Minneapolis, Minnesota, United States, 55455 Less << |
NCT01799590 | Migraine | PHASE2 | COMPLETED | 2025-11-09 | Chitose, Japan|Hachioji, Japan... More >>|Isehara, Japan|Iwate, Japan|Kagoshima, Japan|Kamogawa, Japan|Kitakyushu, Japan|Kobe, Japan|Kumamoto, Japan|Kyoto, Japan|Minato, Japan|Morioka, Japan|Nagoya, Japan|Nishinomiya, Japan|Sagamihara N/A, Japan|Sapporo, Japan|Shinjuku-Ku, Japan|Shizuoka, Japan|Suginami-Ku, Japan|Tokyo, Japan|Toyama, Japan|Toyonaka, Japan|Ube, Japan|Yokohama, Japan|Yonago N/A, Japan Less << |
NCT01145677 | Alcohol Dependence | PHASE2|PHASE3 | COMPLETED | 2025-06-11 | Chiang Mai Drug Dependence Tre... More >>atment Center, Maerim, Chiang Mai, 50180, Thailand|Maharaj Nakorn Chiang Mai Hospital, Muang, Chiang Mai, 50200, Thailand|Suanprung Psychiatric Hospital, Muang, ChiangMai, 50100, Thailand|Maharaj Nakorn Chiang Mai Hospital, Muang, ChiangMai, 50200, Thailand Less << |
NCT01408641 | Alcohol Dependence ... More >> Alcoholism Alcohol Abuse Alcohol Use Disorder PTSD Posttraumatic Stress Disorder Less << | Not Applicable | Terminated(Principal Investiga... More >>tor was deployed overseas) Less << | - | United States, Maryland ... More >> Baltimore VA, VA Maryland Health Care System Baltimore, Maryland, United States, 21201 Less << |
NCT01408641 | - | Terminated(Principal Investiga... More >>tor was deployed overseas) Less << | - | - | |
NCT01135602 | Alcohol Dependence | PHASE4 | UNKNOWN | 2025-03-12 | Maharaj Nakorn Chiang Mai Hosp... More >>ital, Muang, Chiang Mai, 50200, Thailand|Maharaj Nakorn Chiang Mai Hospital, Muang, Chiang Mai, 50200, Thailand Less << |
NCT01799590 | Migraine | PHASE2 | COMPLETED | 2025-11-09 | Chitose, Japan|Hachioji, Japan... More >>|Isehara, Japan|Iwate, Japan|Kagoshima, Japan|Kamogawa, Japan|Kitakyushu, Japan|Kobe, Japan|Kumamoto, Japan|Kyoto, Japan|Minato, Japan|Morioka, Japan|Nagoya, Japan|Nishinomiya, Japan|Sagamihara N/A, Japan|Sapporo, Japan|Shinjuku-Ku, Japan|Shizuoka, Japan|Suginami-Ku, Japan|Tokyo, Japan|Toyama, Japan|Toyonaka, Japan|Ube, Japan|Yokohama, Japan|Yonago N/A, Japan Less << |
NCT02884050 | Alteration of Cognitive Functi... More >>on Less << | Phase 1 | Completed | - | - |
NCT01641445 | Alcohol Drinking | Phase 1 Phase 2 | Unknown | August 2016 | United States, Rhode Island ... More >> Brown University, Center for Alcohol and Addiction Studies Recruiting Providence, Rhode Island, United States, 02912 Contact: Robert Jr. 401-863-6658 Robert_Miranda_Jr@Brown.EDU Contact: Peter Monti 4018636661 Peter_Monti@brown.edu Sub-Investigator: Peter Monti, Ph.D. Sub-Investigator: Jennifer Tidey, Ph.D. Sub-Investigator: Robert Swift, MD, Ph.D. Sub-Investigator: Damaris Rohsenow, Ph.D. Sub-Investigator: Chad Gwaltney, Ph.D. Sub-Investigator: Alicia Justus, Ph.D. Less << |
NCT00846495 | - | Completed | - | - | |
NCT02424318 | Migraine Disorders | PHASE4 | COMPLETED | 2025-12-10 | - |
NCT03018704 | Alcohol Use Disorder | Phase 4 | Recruiting | September 29, 2022 | United States, Pennsylvania ... More >> Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA Recruiting Philadelphia, Pennsylvania, United States, 19104 Contact: David W Oslin, MD 215-823-5870 Dave.Oslin@va.gov Principal Investigator: David W. Oslin, MD Less << |
NCT02810483 | Prader-Willi Syndrome | Phase 3 | Terminated | - | France ... More >> Hôpital La Pitié Salpêtrière Paris, France, 75013 Less << |
NCT02808533 | Schizophrenia, Schizoaffective... More >> Disorder Less << | Not Applicable | Recruiting | December 2018 | Canada, Ontario ... More >> Center for Addiction and Mental Health Recruiting Toronto, Ontario, Canada, M5T 1R8 Contact: Margaret K Hahn, MD 4165358501 ext 34368 margaret.hahn@camh.ca Contact: Zohra A Ahsan, HBSc 4165358501 ext 34103 zohra.ahsan@camh.ca Principal Investigator: Margaret K Hahn, MD, PhD Less << |
NCT00846495 | Migraine | Phase 4 | Completed | - | United States, Florida ... More >> Physician Associates LLC Oviedo, Florida, United States, 32765 United States, Missouri Clinvest Springfield, Missouri, United States, 65807 Less << |
NCT02138058 | Compulsive Shopping | Phase 2 | Completed | - | Brazil ... More >> Associação Viver Bem São Paulo, SP, Brazil, 05404-010 Less << |
NCT03120468 | Alcoholism | Early Phase 1 | Recruiting | April 2018 | United States, Virginia ... More >> UVA Center for Leading Edge Addiction Research Recruiting Charlottesville, Virginia, United States, 22903 Contact: Eva Jenkins-Mendoza 434-243-0562 emj9c@virginia.edu Contact: Tracie Kostelac (434)243-0563 tlk5d@virginia.edu Less << |
NCT02169830 | Migraine Disorders | Not Applicable | Recruiting | December 2020 | United States, Missouri ... More >> Saint Louis University Recruiting Saint Louis, Missouri, United States, 63110 Contact: Deniece D Webb, BA 314-268-7407 deniece.webb@health.slu.edu Contact: Anthony Mikulec, MD 314-577-8884 anthony.mikulec@health.slu.edu Principal Investigator: Anthony Mikulec, MD Less << |
NCT01682681 | Epilepsy | COMPLETED | 2025-05-09 | - | |
NCT02878798 | Cryptogenic Sensory Peripheral... More >> Neuropathy in Metabolic Syndrome Less << | Phase 2 | Recruiting | December 2021 | United States, Alabama ... More >> University of Alabama Birmingham Recruiting Birmingham, Alabama, United States, 35233 Contact: Melanie Benge 205-975-0445 melaniebenge@uabmc.edu Principal Investigator: Eroboghene Ubogu, MD United States, Colorado University of Colorado Denver Recruiting Aurora, Colorado, United States, 80045 Contact: Brianna Blume 303-724-6386 brianna.blume@ucdenver.edu Principal Investigator: Dianna Quan, MD United States, Florida University of Miami Recruiting Miami, Florida, United States, 33136 Contact: Wendy Levy 305-243-6725 wel20@med.miami.edu Principal Investigator: Mario Saporta, MD, PhD United States, Illinois Northwestern University Recruiting Chicago, Illinois, United States, 60611 Contact: Tina Ward 312-503-2128 tina.ward@northwestern.edu Principal Investigator: Daniela Menichella, MD, PhD United States, Kansas University of Kansas Medical Center Recruiting Kansas City, Kansas, United States, 66160 Contact: Chad Parks 913-945-9938 cparks@kumc.edu Principal Investigator: Mamatha Pasnoor, MD United States, Massachusetts Massachusetts General Hospital Recruiting Boston, Massachusetts, United States, 02114 Contact: Peter James 617-643-4218 pfjames@partners.org Principal Investigator: Reza Seyedsadjadi, MD United States, Missouri Washington University School of Medicine Recruiting Saint Louis, Missouri, United States, 63110 Contact: Mengesha Teshome 314-747-8420 teshomem@wustl.edu Principal Investigator: Glenn Lopate, MD United States, New York Columbia University Medical Center Recruiting New York, New York, United States, 10032 Contact: Arruem Kim 212-305-6036 ak3905@cumc.columbia.edu Principal Investigator: Thomas Brannagan, MD University of Rochester Medical Center Recruiting Rochester, New York, United States, 14642 Contact: Janet Sowden 585-275-1267 janet_sowden@urmc.rochester.edu Principal Investigator: David Herrmann, MBBCh, MD United States, Ohio Ohio State University Recruiting Columbus, Ohio, United States, 43221 Contact: Amy Bartlett 614-366-9050 amy.bartlett@osumc.edu Principal Investigator: Amro Stino, MD United States, Tennessee Vanderbilt University Medical Center Recruiting Nashville, Tennessee, United States, 37232 Contact: Kelly Lowen 615-936-0209 kelly.lowen@vumc.org Principal Investigator: Amanda Peltier, MD United States, Texas UT Southwestern Medical Center Not yet recruiting Dallas, Texas, United States, 75390 Contact: Mariam Andersen 214-648-6329 mariam.andersen@utsouthwestern.edu Principal Investigator: Lauren Phillips, MD United States, Virginia Eastern Virginia Medical Center Recruiting Norfolk, Virginia, United States, 23510 Contact: Carolina Caselllini 757-446-7976 casellcm@evms.edu Principal Investigator: Aaron Vinik, MD,PhD Virginia Commonwealth University Not yet recruiting Richmond, Virginia, United States, 23298 Contact: Gordon Smith, MD 804-828-9556 gordon.smith@vcuhealth.org Contact: Brittney A Holmberg 804-658-6439 brittney.holmberg@vcuhealth.org Principal Investigator: Gordon Smith, MD Less << |
NCT01682681 | Epilepsy | COMPLETED | 2025-05-09 | - | |
NCT01381523 | - | Completed | - | - | |
NCT01606813 | Overweight Ob... More >>ese Less << | Not Applicable | Completed | - | United States, Pennsylvania ... More >> Penn State Hershey Medical Center Hershey, Pennsylvania, United States, 17033 Less << |
NCT02727101 | Epilepsy | Phase 4 | Terminated(slow enrollment) | - | United States, Maryland ... More >> MidAtlantic Epilepsy and Sleep Center Bethesda, Maryland, United States, 20817 Less << |
NCT01713946 | Tuberous Sclerosis Complex-ass... More >>ociated Refractory Seizures Less << | Phase 3 | Completed | - | - |
NCT02205931 | Epilepsy | Phase 4 | Recruiting | June 2019 | United Kingdom ... More >> Birmingham Children's Hospital Recruiting Birmingham, United Kingdom, B4 6NH Contact: Shakti Agrawal, MBBS 0044 1213338149 shakti.agrawal@bch.nhs.uk Principal Investigator: Shakti Agrawal, MBBS Bristol Royal Hospital for Children Recruiting Bristol, United Kingdom, BS2 8AE Contact: Andrew Mallick, FRCPCH Principal Investigator: Andrew Mallick Addenbrooke's Hospital Recruiting Cambridge, United Kingdom, CB2 0QQ Contact: Alasdair Parker, MA 0044 1223 245151 alasdair.parker@addenbrookes.nhs.uk Principal Investigator: Alasdair Parker, MA Lancashire Teaching Hospitals NHS Foundation Trust Recruiting Lancashire, United Kingdom Contact: Helen Basu Helen.Basu@lthtr.nhs.uk Principal Investigator: Helen Basu Leeds Teaching Hospital Recruiting Leeds, United Kingdom, LS1 3EX Contact: Helen McCullagh, RCPCH 0044 113 243 2799 h.mccullagh@nhs.net Principal Investigator: Helen McCullagh, RCPCH Alder Hey Children's Hospital Recruiting Liverpool, United Kingdom, L12 2AP Contact: Rachel Kneen, BMBS 0044 151 2525163 rachel.kneen@liverpool.ac.uk Principal Investigator: Rachel Kneen, BMBS Great Ormond Street Hospital Recruiting London, United Kingdom, WC1N 3JH Contact: Christin Eltze, MD Res 0044 207 405 9200 ext 5438 christin.eltze@gosh.nhs.uk Principal Investigator: Christin Eltze, MD Res St George's University Hospitals NHS Foundation Trust Recruiting London, United Kingdom Contact: Penny Fallon Penny.Fallon@stgeorges.nhs.uk Principal Investigator: Penny Fallon Royal Manchester Children's Hospital Recruiting Manchester, United Kingdom, M13 0JE Contact: Tim Martland, RCPCH 0044 161 276 1234 timothy.martland@cmft.nhs.uk Principal Investigator: Tim Martland, RCPCH The Newcastle Upon Tyne Hospitals NHS Foundation Trust Recruiting Newcastle upon Tyne, United Kingdom Contact: Anita Devlin Anita.Devlin@nuth.nhs.uk Principal Investigator: Anita Devlin Sheffield Children's NHS Foundation Trust Recruiting Sheffield, United Kingdom Contact: Archana Desurkar Archana.Desurkar@sch.nhs.uk Principal Investigator: Archana Desurkar Less << |
NCT02707965 | Epilepsy | Phase 4 | Completed | - | United States, Maryland ... More >> University of Maryland, Baltimore Baltimore, Maryland, United States, 21201 Less << |
NCT02607891 | Epilepsy | Phase 2 | Recruiting | August 2018 | France ... More >> Not yet recruiting Elancourt, France Not yet recruiting Paris, France Not yet recruiting Rennes, France Netherlands Not yet recruiting Zwolle, Netherlands Poland Not yet recruiting Kraków, Poland Romania Not yet recruiting Bucuresti, Romania Spain Recruiting Barcelona, Spain Recruiting Madrid, Spain Recruiting Sevilla, Spain Sweden Recruiting Goteborg, Sweden Less << |
NCT01713946 | - | Completed | - | - | |
NCT02374567 | Dementia Depr... More >>ession Schizophrenia Psychosomatic Disorders Anxiety Disorders Less << | Phase 3 | Terminated | - | Germany ... More >> Bezirkskrankenhaus Augsburg Augsburg, Germany Krankenhaus Hedwigshöhe Berlin, Germany Hannover Medical School Hannover, Germany, 30625 Asklepios Fachklinikum Lübben Lübben, Germany Asklepios Fachklinikum Teupitz Teupitz, Germany Less << |
NCT00806260 | Overweight Ob... More >>esity Less << | Phase 2 | Completed | - | United States, Nebraska ... More >> Research Site Lincoln, Nebraska, United States, 68502 Less << |
NCT00659035 | - | Active, not recruiting | July 2020 | United States, Illinois ... More >> Rush University Medical Center Chicago, Illinois, United States, 60612 Less << | |
NCT00404248 | Brain and Central Nervous Syst... More >>em Tumors Less << | Phase 1 Phase 2 | Completed | - | United States, Alabama ... More >> UAB Comprehensive Cancer Center Birmingham, Alabama, United States, 35294-3410 United States, Florida H. Lee Moffitt Cancer Center and Research Institute at University of South Florida Tampa, Florida, United States, 33612-9497 United States, Georgia Winship Cancer Institute of Emory University Atlanta, Georgia, United States, 30322 United States, Maryland Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231 United States, Massachusetts Massachusetts General Hospital Boston, Massachusetts, United States, 02114 United States, Michigan Josephine Ford Cancer Center at Henry Ford Hospital Detroit, Michigan, United States, 48202 United States, North Carolina Wake Forest University Comprehensive Cancer Center Winston-Salem, North Carolina, United States, 27157-1096 United States, Ohio Cleveland Clinic Taussig Cancer Center Cleveland, Ohio, United States, 44195 United States, Pennsylvania Abramson Cancer Center of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104-4283 Less << |
NCT00552526 | Epilepsy Ment... More >>al Retardation Less << | Phase 4 | Unknown | December 2013 | Norway ... More >> SSE, Nevrological dep. , Rikshospitalet University hospital Oslo, Norway Less << |
NCT00806260 | - | Completed | - | - | |
NCT00404248 | - | Completed | - | - | |
NCT03636958 | Refractory Epilepsy | Not Applicable | Not yet recruiting | December 2022 | France ... More >> Assistance Publique Des Hopitaux de Marseille Not yet recruiting Marseille, Paca, France, 13354 Contact: STANISLAS LAGARDE, MD +33 491385554 Stanislas.LAGARDE@ap-hm.fr Less << |
NCT00068770 | Brain and Central Nervous Syst... More >>em Tumors Less << | Phase 2 | Terminated(EORTC trail showed ... More >>TMZ & RT conferred significant survivial in this population) Less << | - | United States, Florida ... More >> H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States, 33612-9497 United States, Georgia Winship Cancer Institute of Emory University Atlanta, Georgia, United States, 30322 United States, Maryland Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231-2410 United States, Massachusetts Massachusetts General Hospital Cancer Center Boston, Massachusetts, United States, 02114-2617 United States, North Carolina Comprehensive Cancer Center at Wake Forest University Winston-Salem, North Carolina, United States, 27157-1030 United States, Ohio Cleveland Clinic Taussig Cancer Center Cleveland, Ohio, United States, 44195 United States, Pennsylvania Abramson Cancer Center of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104-4283 Less << |
NCT00553787 | Obesity Type ... More >>2 Diabetes Less << | Phase 3 | Completed | - | United States, Alabama ... More >> Research Site Birmingham, Alabama, United States, 35294 United States, Connecticut Research Site Ridgefield, Connecticut, United States, 06877 United States, New York Research Site New York, New York, United States, 10025 United States, North Carolina Research Site Durham, North Carolina, United States, 27710 United States, Ohio Research Site Toledo, Ohio, United States, 43623 United States, Texas Research Site Austin, Texas, United States, 78731 Less << |
NCT00553787 | - | Completed | - | - | |
NCT00704860 | Major Depression | Phase 4 | Completed | - | Canada, Ontario ... More >> University of Ottawa Institute of Mental Health Research Ottawa, Ontario, Canada, K1Z 7K4 Less << |
NCT02300051 | Compulsive Sexual Behavior | Not Applicable | Completed | - | Brazil ... More >> Instituto de Psiquiatria do Hospital das Clínicas da Universidade de São Paulo[University of Sao Paulo General Hospital] São Paulo, Brazil, 05403010 Less << |
NCT02403687 | - | Completed | - | - | |
NCT00068770 | - | Terminated(EORTC trail showed ... More >>TMZ & RT conferred significant survivial in this population) Less << | - | - | |
NCT02670161 | Brain Tumors ... More >>Epilepsy Migraine Mild Cognitive Impairment Concussion Multiple Sclerosis Neuropathy Parkinson's Restless Legs Syndrome Stroke Less << | Phase 4 | Enrolling by invitation | April 2020 | - |
NCT00759993 | Weight Gain O... More >>besity Less << | Phase 2 | Terminated(inability to recrui... More >>t and retain) Less << | March 2013 | - |
NCT03671681 | Chronic Migraine ... More >> Medication Overuse Headache Less << | Not Applicable | Not yet recruiting | November 2021 | Italy ... More >> Fondazione IRCCS Istituto Neurologico C. Besta, Neuroalgology Unit Not yet recruiting Milano, Italy, 20133 Contact: Domenico D'Amico, MD domenico.damico@istituto-besta.it Principal Investigator: Domenico D'Amico, MD Less << |
NCT00539188 | Borderline Personality Disorde... More >>r Self-Injurious Behavior Less << | Phase 2 | Terminated(Study terminated du... More >>e to poor subject compliance.) Less << | - | United States, Connecticut ... More >> Yale OCD Research Clinic New Haven, Connecticut, United States, 06519 Less << |
NCT00539188 | - | Terminated(Study terminated du... More >>e to poor subject compliance.) Less << | - | - | |
NCT02499393 | Perinatal Anoxic-ischemic Brai... More >>n Injury Less << | Phase 2 Phase 3 | Completed | - | Poland ... More >> Polish Mother Memorial Hospital - Research Instutiute Lodz, Poland, 93-338 Less << |
NCT03107507 | Neonatal Seizures | Phase 4 | Recruiting | December 30, 2017 | Egypt ... More >> Cairo University Children's Hospital (Abulreesh) Recruiting Cairo Governorate, Egypt Contact: Yara Shaheen Less << |
NCT03050827 | Diabetic; Neuropathic, Polyneu... More >>ropathy (Manifestation) Less << | Phase 3 | Completed | - | United States, Virginia ... More >> Eastern Virgnia Medical School, Strelitz Diabetes Center Norfolk, Virginia, United States, 23510f Less << |
NCT01549288 | Infantile Spasms | Phase 2 Phase 3 | Withdrawn | December 2013 | India ... More >> Lady Hardinge Medical College and Associated Kalawati Saran Children's Hospital New Delhi, Delhi, India, 110001 Less << |
NCT01390909 | - | Completed | - | - | |
NCT00635960 | Amyotrophic Lateral Sclerosis | Phase 2 | Completed | - | Italy ... More >> Diparimento di Scienze Neurologiche Naples, Italy, 80131 Istituto Biostrutture e Bioimmagini, Consiglio Nazionale delle Ricerche Naples, Italy, 80131 Less << |
NCT01390909 | - | Completed | - | - | |
NCT03196466 | - | Recruiting | June 2019 | France ... More >> AP-HP Cochin Recruiting Paris, France, 75014 Contact: Jean-Marc Treluyer, M.D., PhD + 00 1 58 41 28 85 jean-marc.treluyer@parisdescartes.fr Less << | |
NCT00486291 | Type 2 Diabetes Mellitus | Phase 2 | Completed | - | United States, Alabama ... More >> Research Site Birmingham, Alabama, United States United States, California Research Site Los Angeles, California, United States Research Site San Francisco, California, United States Research Site Spring Valley, California, United States Research Site Walnut Creek, California, United States United States, Maryland Research Site Bethesda, Maryland, United States United States, Texas Research Site Austin, Texas, United States Research Site San Antonio, Texas, United States United States, Virginia Research Site Richmond, Virginia, United States Less << |
NCT02429596 | Epilepsy | Phase 4 | Unknown | May 2015 | Italy ... More >> Clinica Neurologica, Ospedali Riuniti Not yet recruiting Ancona, Italy Contact: Leandro Provinciali, MD leandroprovinciali@gmail.com Clinica Neurologica Amaducci, Policlinico di Bari Not yet recruiting Bari, Italy Contact: Angela La Neve, MD centroepilessia@neurol.uniba.it Principal Investigator: Angela La Neve, MD U.S.C. Neurologia, Ospedali Riuniti Active, not recruiting Bergamo, Italy Dipartimento di Scienze Neurologiche, Università degli Studi di Bologna Recruiting Bologna, Italy Contact: Agostino Baruzzi, MD agostino.baruzzi@unibo.it Contact: Barbara Mostacci, MD barbara.mostacci@unibo.it Principal Investigator: Agostino Baruzzi, MD Unità Operativa Complessa di Neurologia, Ospedale di Bellaria Recruiting Bologna, Italy Contact: Roberto Michelucci, MD roberto.michelucci@ausl.bologna.it Contact: Lilia Volpi, MD lilia.volpi@ausl.bologna.it Centro Regionale dell'Epilessia, Azienda Ospedaliera Spedali Civili Not yet recruiting Brescia, Italy Contact: Luisa Antonini, MD luisa.antonini@spedalicivili.brescia.it Azienda Ospedaliera, Policlinico Universitario Mater Domini Completed Catanzaro, Italy, 88100 Azienda Ospedaliera ospedali Riuniti Active, not recruiting Foggia, Italy Azienda Ospedaliera Universitaria Policlinico Gaetano Martino Not yet recruiting Messina, Italy Contact: Edoardo Spina, MD espina@unime.it Principal Investigator: Edoardo Spina, MD Clinica Neurologica, Ospedale San Gerardo Not yet recruiting Monza, Italy Contact: Carlo Ferrarese, MD carlo.ferrarese@unimib.it Contact: Simone Beretta, MD simone.beretta@unimib.it Clinica Neurologica, Azienda Ospedaliero-Universitaria Maggiore della Carità Recruiting Novara, Italy Contact: Roberto Cantello, MD Contact: Claudia Varrasi, MD claudia.varrasi@libero.it S.C. di Neurofisiopatologia, Centro di Riferimento Regionale Umbro per l'Epilessia Not yet recruiting Perugia, Italy Contact: Teresa Anna Cantisani, MD cantisani@yahoo.com UO di Neurologia, Azienda Ospedaliero Universitaria Pisana Active, not recruiting Pisa, Italy Centro Regionale Epilessie, Reggio Calabria e Università della Magna Graecia Recruiting Reggio Calabria, Italy Contact: Umberto Aguglia, MD u.aguglia@tin.it Contact: Sara Gasparini, MD Dipartimento di Scienze Neurologiche, III Clinica Neurologica, Università "La Sapienza" Not yet recruiting Roma, Italy Contact: Anna Teresa Giallonardo, MD annateresa.giallonardo@uniroma1.it Unità Complessa di Neurologia, Ospedale SS. Giovanni e Paolo Not yet recruiting Venezia, Italy Contact: Francesco Paladin, MD Less << |
NCT00004807 | Rett Syndrome | Not Applicable | Completed | - | - |
NCT00745251 | Sleep Apnea | Phase 1 Phase 2 | Completed | - | United States, Kentucky ... More >> Kentucky Research Group Louisville, Kentucky, United States, 40217 Less << |
NCT01000402 | Bipolar Disorder ... More >> Attention Deficit Disorder With Hyperactivity Less << | Phase 4 | Unknown | November 2014 | Brazil ... More >> Hospital de Clinicas de Porto Alegre Recruiting Porto Alegre, RS, Brazil, 90350-903 Contact: Clarissa F Paim +55 51 21018094 cfpaim@hcpa.ufrgs.br Contact: Silza Tramontina, D.Sc. +55 51 21018094 silza.tramontina@terra.com.br Principal Investigator: Luis A Rohde, D.Sc. Sub-Investigator: Silza Tramontina, D.Sc. Sub-Investigator: Cristian P Zeni, M.Sc. Sub-Investigator: Carla R Ketzer, M.Sc. Sub-Investigator: Gabriel F Pheula, MD Sub-Investigator: Fernanda V Krieger, MD Sub-Investigator: Sandra Petresco, M.Sc. Sub-Investigator: Roberta S Coelho, B.Sc. Sub-Investigator: Adriana F Perez, M.Sc. Sub-Investigator: Lanuzia Brum, BA Sub-Investigator: Ana P Guimaraes, M.Sc. Sub-Investigator: Henrique T Ludwig Less << |
NCT00241995 | Topiramate La... More >>motrigine Memnatine Diazepam Placebo Less << | Not Applicable | Completed | - | - |
NCT02993861 | - | Recruiting | September 2018 | United States, Colorado ... More >> The Children's Hospital Colorado Not yet recruiting Aurora, Colorado, United States, 80045 Contact: Austin Drake 720-777-4719 austin.drake@childrenscolorado.org Contact: Charuta Joshi, MD 1-720-777-6895 charuta.joshi@childrenscolorado.org United States, Delaware Nemours Alfred I. DuPont Hospital for Children Recruiting Wilmington, Delaware, United States, 19803 Contact: Ramany John 302-298-7521 ramany.john@nemours.org Contact: Marisa Meyer, MD 1-302-651-4021 marisa.meyer@nemours.org United States, Georgia Childrens Healthcare of Atlanta Recruiting Atlanta, Georgia, United States, 30324 Contact: Sims Christopher 404-785-8798 christopher.sims@choa.org Contact: Ton DeGrauw, MD 1-404-785-4446 ton.degrauw@choa.org United States, Illinois Ann and Robert H. Lurie Children's Hospital of Chicago Recruiting Chicago, Illinois, United States, 60611 Contact: Laura Fearn 312-227-6280 lfearn@luriechildrens.org Contact: William Muller, MD 312-503-3218 wjmuller@northwestern.edu United States, Kentucky University of Louisville Norton Childrens Hospital Recruiting Louisville, Kentucky, United States, 40202 Contact: Terri Simeon 502-629-5820 theresa.simeon@louisville.edu Contact: Arpita Lakhotia, MD 1-502-629-5820 arpita.lakhotia@louisville.edu United States, North Carolina University of North Carolina at Chapel Hill Recruiting Chapel Hill, North Carolina, United States, 27514 Contact: Shradhdha Joshi 919-966-9051 snjoshi@neurology.unc.edu Contact: Yael Shiloh-Malawsky, MD 919-966-2922 yaelm@neurology.unc.edu Duke University Health System Recruiting Durham, North Carolina, United States, 27705 Contact: Kanecia Zimmerman, MD 919-668-8651 kanecia.obie@dm.duke.edu Contact: Harward Melissa 919-668-3910 melissa.harward@dm.duke.edu Coastal Children's Services Not yet recruiting Wilmington, North Carolina, United States, 28401 Contact: Arielle Lapid 910-667-5483 arielle.lapid@ccneo.net Contact: Sasidharan Taravath, MD 1-910-667-5165 sasi.taravath@coastalchildrensservices.net United States, Oregon Oregon Health and Science University Recruiting Portland, Oregon, United States Contact: Kira Clark 503-418-8112 clarki@ohsu.edu Contact: Amira Al-Uzri 1-503-494-6956 aluzria@ohsu.edu United States, Texas University of Texas Southwestern Medical Center Dallas Recruiting Dallas, Texas, United States, 75390-8589 Contact: Susan Arnold, MD 214-456-8242 susan.arnold@utsouthwestern.edu United States, Washington Seattle Children's Hospital Not yet recruiting Seattle, Washington, United States, 98105 Contact: Megan Kelton 206-987-5539 megan.kelton@seattlechildrens.org Contact: Joseph Flynn, MD 1-206-987-2524 joseph.flynn@seattlechildrens.org Less << | |
NCT00745251 | - | Completed | - | - | |
NCT03374956 | Obesity | Phase 3 | Recruiting | December 1, 2020 | United States, Minnesota ... More >> Mayo Clinic in Rochester Recruiting Rochester, Minnesota, United States, 55905 Contact: Judith Davis 507-266-9447 RSTINDIVOBESITY@mayo.edu Principal Investigator: Andres J Acosta Less << |
NCT00796367 | Obesity | Phase 3 | Completed | - | - |
NCT00796367 | - | Completed | - | - | |
NCT03689114 | Epilepsies, Partial | Phase 4 | Not yet recruiting | December 2021 | - |
NCT00737633 | - | Terminated(Limited regulatory ... More >>value to uncontrolled trials. No safety/efficacy concerns.) Less << | - | - | |
NCT02229214 | Obesity | Phase 4 | Completed | - | United States, Colorado ... More >> Research Center Lakewood, Colorado, United States, 80228 Less << |
NCT00486291 | - | Completed | - | - | |
NCT02229214 | - | Completed | - | - | |
NCT00777218 | Migraine | Not Applicable | Unknown | July 2011 | United States, Alabama ... More >> University of South Alabama Department of Neurology Recruiting Mobile, Alabama, United States, 36693 Sub-Investigator: Maher Loutfi, MD Less << |
NCT00768209 | Hepatic Impairment | Phase 1 | Completed | - | United States, Florida ... More >> Clinical Pharmacology of Miami Miami, Florida, United States, 33014-3616 Orlando Clinical Research Center Orlando, Florida, United States, 32809-3017 Less << |
NCT01351753 | Obesity Metab... More >>olic Syndrome X Less << | Phase 2 | Suspended(Change of staff) | October 2019 | United States, Iowa ... More >> University of Iowa Hospitals and Clinics Iowa City, Iowa, United States, 52241 Less << |
NCT02497443 | Epilepsy | Phase 1 Phase 2 | Active, not recruiting | December 2019 | - |
NCT03461874 | Migraine Without Aura | Not Applicable | Recruiting | July 15, 2021 | Italy ... More >> Fondazione IRCCS Istituto Neurologico C. Besta, Neuroalgology Unit Recruiting Milano, Italy, 20133 Contact: Licia Grazzi, MD licia.grazzi@istituto-besta.it Principal Investigator: Licia Grazzi, MD Less << |
NCT00554216 | Obesity | Phase 3 | Completed | - | United States, California ... More >> Research Site San Diego, California, United States, 92130 United States, Connecticut Research Ridgefield, Connecticut, United States, 06877 United States, North Carolina Research Site Durham, North Carolina, United States, 27710 United States, Ohio Research Site Toledo, Ohio, United States, 43623 United States, Texas Research Site Austin, Texas, United States, 78731 Less << |
NCT01922934 | - | Completed | - | - | |
NCT03125525 | - | Completed | - | - | |
NCT00554216 | - | Completed | - | - | |
NCT00563368 | Obesity | Phase 3 | Completed | - | United States, North Carolina ... More >> Research Site Durham, North Carolina, United States United States, Pennsylvania Research Site Philadelphia, Pennsylvania, United States Less << |
NCT01922934 | Obesity | Phase 4 | Completed | - | United States, Colorado ... More >> Denver Health and Hospital Authority Denver, Colorado, United States, 80204 Less << |
NCT00731900 | - | Unknown | December 2009 | Taiwan ... More >> National Taiwan University Hospital Recruiting Taipei, Taiwan, 100 Contact: Horng-Huei Liou, MD;PhD 886-2-23123456 ext 8325 hhl@ntu.edu.tw Less << | |
NCT00563368 | - | Completed | - | - | |
NCT02645370 | Migraine | Phase 1 | Unknown | - | China, Shanxi ... More >> Xijing Hospital Not yet recruiting Xi'an, Shanxi, China, 710032 Less << |
NCT00737633 | Diabetes | Phase 2 | Terminated(Limited regulatory ... More >>value to uncontrolled trials. No safety/efficacy concerns.) Less << | - | United States, Alabama ... More >> Research Site Birmingham, Alabama, United States United States, California Research Site Los Angeles, California, United States Research Site San Francisco, California, United States Research Site Spring Valley, California, United States Research Site Walnut Creek, California, United States United States, Maryland Research Site Bethesda, Maryland, United States United States, Texas Research Site Austin, Texas, United States Research Site San Antonio, Texas, United States United States, Virginia Research Site Richmond, Virginia, United States Less << |
NCT02714062 | - | Completed | - | - | |
NCT01161017 | Migraine | Not Applicable | Completed | - | Israel ... More >> Rambam Medical Center Haifa, Israel Less << |
NCT00600067 | Diabetes | Phase 2 | Completed | - | United States, Alabama ... More >> Research Site Birmingham, Alabama, United States United States, California Research Site Los Angeles, California, United States Research Site San Francisco, California, United States Research Site Spring Valley, California, United States Research Site Walnut Creek, California, United States United States, Maryland Research Site Bethesda, Maryland, United States United States, Texas Research Site Austin, Texas, United States Research Site San Antonio, Texas, United States United States, Virginia Research Site Richmond, Virginia, United States Less << |
NCT00600067 | - | Completed | - | - | |
NCT00001725 | Facial Neuralgia ... More >> Pain Trigeminal Neuralgia Less << | Phase 2 | Completed | - | United States, Maryland ... More >> National Institute of Dental And Craniofacial Research (NIDCR) Bethesda, Maryland, United States, 20892 Less << |
NCT00862095 | Headache | Phase 4 | Terminated(inadequate enrollme... More >>nt, insufficient funds to continue enrollment) Less << | - | United States, Washington ... More >> Madigan Army Medical Center Tacoma, Washington, United States, 98431 Less << |
NCT02714062 | Pediatric Obesity ... More >> Childhood Obesity Less << | Phase 4 | Completed | - | United States, Louisiana ... More >> Research Facility Baton Rouge, Louisiana, United States, 70808 Research Facility Marrero, Louisiana, United States, 70072 United States, Ohio Research Facility Cincinnati, Ohio, United States, 45229 United States, South Carolina Research Facility Charleston, South Carolina, United States, 29403 Less << |
NCT02635386 | Polycystic Ovary Syndrome ... More >> Obesity Less << | Phase 3 | Recruiting | August 2019 | United States, Louisiana ... More >> Woman's Hospital Recruiting Baton Rouge, Louisiana, United States, 70815 Contact: Karen Elkind-Hirsch, PhD. 225-231-5278 Contact: Ericka Seidemann, MS 225-231-5275 ericka.seidemann@womans.org Principal Investigator: Karen Elkind-Hirsch, Ph.D. Sub-Investigator: Renee Harris, M.D. Less << |
NCT02945839 | Migraine | Phase 4 | Not yet recruiting | December 2018 | United States, New York ... More >> New York University School of Medicine Not yet recruiting New York, New York, United States, 10016 Contact: Liliana Serrano Liliana.Serrano2@nyumc.org Principal Investigator: mia Minen, MD Less << |
NCT00563459 | Epilepsy Seiz... More >>ures Less << | Phase 3 | Terminated(Carisbamate partial... More >> onset seizures studies lacked consistent efficacy data so trials in this indication were terminated.) Less << | - | - |
NCT03307863 | Contraception ... More >> Drug Interactions Less << | Phase 4 | Recruiting | July 2019 | Brazil ... More >> Hospital das Clínicas de Ribeirão Preto da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo Recruiting Ribeirão Preto, Sao Paulo, Brazil, 14049-900 Contact: Carolina S Vieira, MD +551636022818 carol.sales@usp.br Contact: Leticia S Ferreira, MD +553491924258 lelezinhasanchez1@yahoo.com.br Principal Investigator: Carolina S Vieira, MD Less << |
NCT00772031 | - | Completed | - | - | |
NCT00208858 | Tobacco Use Disorder | PHASE2 | COMPLETED | 2025-12-06 | Atlanta VA Medical Center, Dec... More >>atur, Georgia, 30033, United States Less << |
NCT02643719 | Migraine | Not Applicable | Withdrawn(Study team missed co... More >>ntinuing review and study lapsed with out recruiting any subjects.) Less << | - | - |
NCT00768404 | Renal Impairment | Phase 1 | Completed | - | United States, California ... More >> Advanced Clinical Research Institute Anaheim, California, United States, 92801 United States, Florida Clinical Pharmacology of Miami Miami, Florida, United States, 33014-3616 Orlando Clinical Research Center Orlando, Florida, United States, 32809-3017 United States, Minnesota DaVita Clinical Research Minneapolis, Minnesota, United States, 55404 Less << |
NCT01096420 | Patients With Chronic Migraine | Not Applicable | Completed | - | Taiwan ... More >> Kuang Tien General Hospital Taichung, Taiwan, 433 Less << |
NCT00772031 | Chronic Migraine | Phase 3 | Completed | - | - |
NCT02659475 | Binge Eating Disorder | Phase 2 | Completed | - | United States, Ohio ... More >> Lindner Center of HOPE Mason, Ohio, United States, 45040 Less << |
NCT00006205 | Alcoholism | Phase 2 | Unknown | December 2013 | United States, Virginia ... More >> University of Virginia Center for Addiction Research and Education Recruiting Charlottesville, Virginia, United States, 22911 Contact: Mindy Borszich 888-882-2345 mcb3x@virginia.edu Contact: Eva Jenkins-Mendoza (434)243-0562 emj9c@virginia.edu Principal Investigator: Bankole Johnson, DSc, MD, PhD Sub-Investigator: Nassima Ait-Daoud Tiouririne, MD University of Virginia Center for Addiction Research and Education Recruiting Richmond, Virginia, United States, 23294 Contact: Mindy Borszich 888-882-2345 mcb3x@virginia.edu Contact: Eva Jenkins-Mendoza (434)243-0562 emj9c@virginia.edu Principal Investigator: Bankole Johnson, DSc, MD, PhD Sub-Investigator: Nassima Ait-Daoud Tiouririne, MD Less << |
NCT03603080 | Obesity | Phase 4 | Not yet recruiting | November 1, 2019 | United States, Connecticut ... More >> Hartford Hospital Not yet recruiting Hartford, Connecticut, United States, 06102 Contact: Pavlos K Papasavas, MD 860-246-2071 pavlos.papasavas@hhchealth.org Contact: Darren Tishler, MD 8605244566 darren.tishler@hhchealth.org Sub-Investigator: Pavlos K Papasavas, MD Sub-Investigator: Darren Tishler, MD Principal Investigator: Devika Umashanker, MD Less << |
NCT00571246 | Alcohol Dependence ... More >> Post Traumatic Stress Disorder Less << | Phase 3 | Withdrawn | June 2016 | United States, Connecticut ... More >> VA Connecticut Healthcare System West Haven, Connecticut, United States, 06516 Less << |
NCT02301416 | Obesity Metab... More >>olic Surgery Weight Loss Bariatric Surgery Procedures Less << | Phase 2 | Completed | - | United States, North Carolina ... More >> Wake Forest Baptist Health Winston-Salem, North Carolina, United States, 27157 Less << |
NCT02553824 | Binge Eating Disorder ... More >> Bulimia Nervosa Less << | Phase 1 | Completed | - | United States, California ... More >> Stanford School of Medicine, Psychiatry and Behavioral Sciences Stanford, California, United States, 94305 Less << |
NCT00855738 | Focal Epilepsy | Phase 4 | Completed | - | - |
NCT00217295 | Multiple Sclerosis | Phase 2 | Unknown | - | United States, Pennsylvania ... More >> Multiple Sclerosis Institute Recruiting Philadelphia, Pennsylvania, United States, 19146 Contact: Jeffrey I Greenstein, MD 215-985-2245 Contact: Iris J Gold, MBA 215-985-2245 Principal Investigator: Jeffrey I Greenstein, MD Less << |
NCT00855738 | - | Completed | - | - | |
NCT00154076 | Epilepsy | Phase 4 | Completed | - | Korea, Republic of ... More >> Daegu Catholic University Medical Center Daegu, Korea, Republic of Less << |
NCT00396734 | Opioid-Related Disorders ... More >> Cocaine-Related Disorders Less << | Not Applicable | Suspended(Grant was not renewe... More >>d) Less << | April 2011 | Israel ... More >> Hadassah Medical Organization Jerusalem, Israel, 91120 Less << |
NCT00432549 | Analgesic Rebound Headache | Phase 4 | Unknown | - | United States, Connecticut ... More >> The New England Center for Headache, P.C. Recruiting Stamford, Connecticut, United States, 06902 Principal Investigator: Fred D Sheftell, M.D. Less << |
NCT00208130 | Post-Traumatic Stress Disorder | PHASE4 | COMPLETED | 2025-03-04 | Creighton University Psychiatr... More >>y and Research Center, Omaha, Nebraska, 68131, United States Less << |
NCT04401137 | Migraine | PHASE1 | COMPLETED | 2020-10-06 | Seoul National University Hosp... More >>ital, Dept. of Clinical Pharmacology, Seoul, Korea, Republic of Less << |
NCT00131443 | Basilar Migraine | PHASE2|PHASE3 | COMPLETED | 2025-08-06 | Monarch Medical Research - Chi... More >>ld and Adolescent Neurology, Norfolk, Virginia, 23510, United States Less << |
NCT00065923 | Prader-Willi Syndrome|Self-Inj... More >>urious Behavior Less << | COMPLETED | - | University of Florida-Brain In... More >>stitute, Gainesville, Florida, 32609, United States Less << | |
NCT00297323 | Seizures, Epileptic | COMPLETED | 2025-02-07 | - | |
NCT00035230 | Bipolar Disorder | PHASE3 | COMPLETED | 2025-11-02 | - |
NCT06282783 | HIV-1-infection|Hiv|HIV Infect... More >>ions|HIV I Infection Less << | PHASE1|PHASE2 | NOT_YET_RECRUITING | 2025-08-25 | Erasmus Medical Centre, Rotter... More >>dam, Netherlands Less << |
NCT00223639 | Alcoholism | PHASE2 | COMPLETED | 2025-07-08 | UVA CARE, Charlottesville, Vir... More >>ginia, 22911, United States|UVA CARE Richmond, Richmond, Virginia, 23294, United States Less << |
NCT00212810 | Migraine|Headache|Classic Migr... More >>aine|Common Migraine Less << | PHASE4 | COMPLETED | 2025-08-07 | - |
NCT00203190 | Cluster Headache | PHASE4 | TERMINATED | 2025-06-06 | Jefferson Headache Center, Phi... More >>ladelphia, Pennsylvania, 19107, United States Less << |
NCT00200941 | Restless Legs Syndrome | PHASE4 | COMPLETED | 2025-04-05 | Neurocare, Newton, Massachuset... More >>ts, 02459, United States Less << |
NCT00286923 | Migraine|Chronic Headache | UNKNOWN | 2025-08-06 | Swedish Headache Clinic, Seatt... More >>le, Washington, 98104, United States Less << | |
NCT00187928 | Obsessive-Compulsive Disorder | PHASE3 | COMPLETED | 2025-03-06 | UF Health Science Center, Gain... More >>esville, Florida, 32608, United States Less << |
NCT00011804 | Sciatica | PHASE2 | COMPLETED | 2025-02-05 | National Institute of Dental A... More >>nd Craniofacial Research (NIDCR), Bethesda, Maryland, 20892, United States Less << |
NCT00037674 | Bipolar Disorder | PHASE3 | COMPLETED | 2025-05-03 | - |
NCT00158002 | Basilar Migraine | PHASE2 | COMPLETED | 2025-08-06 | Monarch Medical Research - Chi... More >>ld and Adolescent Neurology, Norfolk, Virginia, 23510, United States Less << |
NCT00286988 | Vomiting | PHASE4 | TERMINATED | 2025-06-07 | Monarch Medical Research - Chi... More >>ld and Adolescent Neurology, Norfolk, Virginia, 23510, United States Less << |
NCT00204386 | Posttraumatic Stress Disorder | PHASE2|PHASE3 | COMPLETED | 2025-05-07 | The University of Oklahoma Hea... More >>lth Sciences Center, Oklahoma City, Oklahoma, 73104, United States Less << |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
2.95mL 0.59mL 0.29mL |
14.73mL 2.95mL 1.47mL |
29.47mL 5.89mL 2.95mL |
|
Dissolving Methods |
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:
in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day; The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
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