Indole Derivatives

Indole, is classified as an aromatic heterocyclic compound. It features a bicyclic structure, which includes a six-carbon benzene ring fused to a five-carbon pyrrole ring. Indole is abundant in nature, predominantly found as the amino acid tryptophan and the neurotransmitter serotonin. Within the core structure of a drug, the indole nucleus engages in key interactions such as acting as a hydrogen bond donor and participating in π-π stacking or cation-π interactions with the target protein. The indole structure is highly favored in drug discovery, with over 17 marketed drugs containing indole, the majority of which are kinase inhibitors. Specifically, the amino- and diamino-indole fragments are particularly common in these drugs. AmBeed provides a collection of indole derivatives intended for pharmaceutical development.

Indole Derivatives

2,3,4,9-Tetrahydro-1H-carbazole
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A101605942-01-898%

2,3,4,9-Tetrahydro-1H-carbazole

$55.0/100g Detail

H-D-Trp-OH
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A101619153-94-697%

H-D-Trp-OH

$207.0/1kg Detail

Tetrahydro-β-carboline
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A10179116502-01-597%

Tetrahydro-β-carboline

$84.0/25g Detail

L-Tryptophan Methyl Ester HCl
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A1018757524-52-998%

L-Tryptophan Methyl Ester HCl

$28.0/100g Detail

5-Methoxyindole
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A1050851006-94-699%

5-Methoxyindole

$20.0/5g Detail

5-Chloro-7-nitro-1H-indole
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A1061981197181-29-597%

5-Chloro-7-nitro-1H-indole

$233.0/10g Detail

Methyl indole-4-carboxylate
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A10736539830-66-598%

Methyl indole-4-carboxylate

$6.0/1g Detail

Methyl 6-fluoro-1H-indole-4-carboxylate
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A1078631082040-43-497%

Methyl 6-fluoro-1H-indole-4-carboxylate

$38.0/1g Detail

Indole-5-carboxaldehyde
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A1095011196-69-698%

Indole-5-carboxaldehyde

$15.0/5g Detail

Fmoc-D-Trp-OH
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A11027386123-11-797%

Fmoc-D-Trp-OH

$274.0/500g Detail

GW 441756
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A110513504433-23-298%

GW 441756

$750.0/1g Detail

Methyl 2-(1H-indol-3-yl)acetate
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A1108951912-33-097%

Methyl 2-(1H-indol-3-yl)acetate

$10.0/1g Detail

4-(Piperazin-1-yl)-1H-indole
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A11168184807-09-097%

4-(Piperazin-1-yl)-1H-indole

$107.0/250mg Detail

4-Bromo-7-methyl-1H-indole
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A111712936092-87-495%

4-Bromo-7-methyl-1H-indole

$867.0/10g Detail

2-Bromo-9H-carbazole
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A1120613652-90-298%

2-Bromo-9H-carbazole

$39.0/25g Detail

3,6-Diphenyl-9H-carbazole
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A11316756525-79-298%

3,6-Diphenyl-9H-carbazole

$8.0/5g Detail

9-(2-Bromophenyl)-9H-carbazole
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A113678902518-11-097%

9-(2-Bromophenyl)-9H-carbazole

$14.0/5g Detail

Methyl 1H-indole-5-carboxylate
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A1140741011-65-098%

Methyl 1H-indole-5-carboxylate

$65.0/25g Detail

GSK126
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A1145681346574-57-998%

GSK126

$48.0/10mg Detail

LY2090314
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A115111603288-22-899%

LY2090314

$306.0/50mg Detail

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