Chemistry Organic Building Blocks Fluorinated Building Blocks 1-fluoro-2-isopropoxybenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—OCH(CH3)CH3).
Cross-Coupling Reactions: Fluorobenzene can be utilized in cross-coupling reactions, such as Suzuki-Miyaura, Negishi, and Stille reactions. These reactions involve coupling a halogenated aromatic compound with an organometallic reagent, resulting in the formation of new carbon-carbon bonds.
Acid-Catalyzed Cleavage: Under acidic conditions, isopropoxybenzene can undergo cleavage of the ether bond to form the corresponding 【alcohol|https://www.ambeed.com/alcohols.html】 and 【phenol|https://www.ambeed.com/phenols.html】. This reaction is known as hydrolysis.
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(3-(Trifluoromethyl)pyridin-2-yl)methanamine hydrochloride
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N-Methyl-1-(6-(trifluoromethyl)pyridin-3-yl)methanamine