Home Chemistry Organic Building Blocks Bromides (2-Bromo-6-Fluorophenyl)Methanol
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—CH2OH,—F).
Suzuki-Miyaura Coupling: Bromobenzene can participate in cross-coupling reactions with organoboron compounds in the presence of a palladium catalyst, resulting in the formation of biaryl compounds.
Cyanation: Phenylmethanol can react with a cyanide source to form benzyl cyanides (benzyl nitriles) in the presence of a base.
Cross-Coupling Reactions: Fluorobenzene can be utilized in cross-coupling reactions, such as Suzuki-Miyaura, Negishi, and Stille reactions. These reactions involve coupling a halogenated aromatic compound with an organometallic reagent, resulting in the formation of new carbon-carbon bonds.
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(6-Bromo-2-fluoro-3-(trifluoromethyl)phenyl)methanol
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(6-Bromo-2-fluoro-3-methylphenyl)methanol
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