Home Chemistry Organic Building Blocks Fluorinated Building Blocks (4-Fluorophenyl)Boronic Acid
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—B(OH)2).
Metalation Reactions: Fluorobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Formation of 【esters|https://www.ambeed.com/esters.html】 and 【Amides|https://www.ambeed.com/amides.html】: Phenylboronic acid can react with 【alcohols|https://www.ambeed.com/alcohols.html】 or 【amines|https://www.ambeed.com/amines.html】 to form 【esters|https://www.ambeed.com/esters.html】 and 【amides|https://www.ambeed.com/amides.html】, respectively, under appropriate conditions.
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(4-Fluoro-2-propoxyphenyl)boronic acid
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(2-(ethoxymethyl)-4-fluorophenyl)boronic acid
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(3,4-Difluoro-2-methoxyphenyl)boronic acid
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(2-Chloro-4-fluoro-3-methoxyphenyl)boronic acid
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(2-((dimethylamino)methyl)-4-fluorophenyl)boronic acid
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(2,4-Difluoro-3-methoxyphenyl)boronic acid
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(3-Ethoxy-4-fluoro-5-(trifluoromethyl)phenyl)boronic acid
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