Home Chemistry Organic Building Blocks Trifluoromethyls (Trifluoromethyl)Benzene
These compounds have the same murcko framework: benzene,and at least 1 kind of functional groups( —CF3).
Nucleophilic Aromatic Substitution (SNAr): Depending on the nature of the nucleophile, nucleophilic aromatic substitution reactions can occur. The trifluoromethyl group can influence the reactivity and regioselectivity of these reactions.
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1-(Chloromethyl)-3,5-bis(trifluoromethyl)benzene
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3,5-Bis(trifluoromethyl)benzenesulfonamide
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(E)-3-(3-(Trifluoromethyl)phenyl)acryloyl chloride
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1-(Trichloromethyl)-3-(trifluoromethyl)benzene
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1-(2-Bromo-1,1,2,2-tetrafluoroethoxy)-3-(trifluoromethyl)benzene
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4-(Chloromethyl)-1-isopropoxy-2-(trifluoromethyl)benzene
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2,3-Difluoro-6-(trifluoromethyl)benzonitrile
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1-(4-Bromo-2-(trifluoromethyl)phenyl)ethanone
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(S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethanol
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