Home Chemistry Organic Building Blocks Trifluoromethyls (Trifluoromethyl)Benzene
These compounds have the same murcko framework: benzene,and at least 1 kind of functional groups( —CF3).
Nucleophilic Aromatic Substitution (SNAr): Depending on the nature of the nucleophile, nucleophilic aromatic substitution reactions can occur. The trifluoromethyl group can influence the reactivity and regioselectivity of these reactions.
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2-Cyano-N-(4-(trifluoromethyl)phenyl)acetamide
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2-Fluoro-4-nitro-1-(trifluoromethyl)benzene
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(R)-3-((tert-Butoxycarbonyl)amino)-3-(4-(trifluoromethyl)phenyl)propanoic acid
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(E)-4-(4-(Trifluoromethyl)phenyl)but-3-en-2-one
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1-(4-(Trifluoromethyl)phenyl)butane-1,3-dione
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1-(4-Chloro-2-(trifluoromethyl)phenyl)ethanone
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(S)-3-((tert-Butoxycarbonyl)amino)-3-(4-(trifluoromethyl)phenyl)propanoic acid
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(S)-2-Amino-3-(3-(trifluoromethyl)phenyl)propanoic acid
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(S)-2-((tert-Butoxycarbonyl)amino)-3-(2-(trifluoromethyl)phenyl)propanoic acid
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