Home Chemistry Heterocyclic Building Blocks Oxazolines 1,3-Bis(4,5-Dihydrooxazol-2-Yl)Benzene
Electrophilic Aromatic Substitution: The benzene ring in 1,3-bis(4,5-dihydrooxazol-2-yl)benzene can undergo electrophilic aromatic substitution reactions, where it can react with electrophiles to substitute one of its hydrogen atoms. Common electrophiles include halogens (e.g., bromine or chlorine) and nitro groups.
Nucleophilic Substitution: If the oxazole rings contain suitable leaving groups, nucleophilic substitution reactions can occur. Nucleophiles can attack the leaving group in the oxazole ring to replace it with the nucleophile.
Reduction: The oxazole rings may be reduced using reducing agents to form dihydrooxazoles or other reduced products.
Oxidation: Oxidizing agents can be used to convert the oxazole rings into oxazoles or other oxidized products.
Cross-Coupling Reactions: 1,3-bis(4,5-dihydrooxazol-2-yl)benzene can be used in cross-coupling reactions, such as Suzuki coupling, Heck reaction, or Sonogashira coupling, to form carbon-carbon or carbon-heteroatom bonds.
Ring Opening: Under certain conditions, the oxazole rings can undergo ring-opening reactions, which may result in the formation of open-chain compounds or other products.
Acid-Base Reactions: The oxazole rings contain basic nitrogen atoms that can undergo acid-base reactions with suitable acids or bases.
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1,3-Bis((S)-4-isobutyl-4,5-dihydrooxazol-2-yl)benzene
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1,3-Bis((R)-4-isobutyl-4,5-dihydrooxazol-2-yl)benzene
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1,3-Bis((S)-4-((S)-sec-butyl)-4,5-dihydrooxazol-2-yl)benzene
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1,3-Bis((S)-4-(tert-butyl)-4,5-dihydrooxazol-2-yl)benzene
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1,3-Bis((S)-4-isopropyl-4,5-dihydrooxazol-2-yl)benzene
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1,3-Bis((R)-4-isopropyl-4,5-dihydrooxazol-2-yl)benzene
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1,3-Bis((R)-4-(tert-butyl)-4,5-dihydrooxazol-2-yl)benzene
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