Home Chemistry Organic Building Blocks Fluorinated Building Blocks 1-(3-Fluorophenyl)Ethan-1-One
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—C(O)CH3).
Fluorine Substitution: Fluorobenzene can undergo further substitution reactions to replace the fluorine atom with other functional groups. This can be achieved through nucleophilic aromatic substitution reactions. The electron-withdrawing nature of fluorine can affect the regioselectivity and reactivity of such substitutions.
Acylation Reactions: Acetophenone can undergo acylation reactions with 【acid chlorides|https://www.ambeed.com/acyl-chlorides.html】 or 【anhydrides|https://www.ambeed.com/anhydrides.html】 in the presence of a Lewis acid catalyst to form diaryl 【ketones|https://www.ambeed.com/ketones.html】.
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Methyl 2-(4-acetyl-2-fluorophenyl)acetate
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(4-Acetyl-2-fluorophenyl)boronic acid
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1-(3,5-Difluoro-2-hydroxyphenyl)ethanone
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1-(4-Bromo-3,5-difluorophenyl)ethanone
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1-(5-Fluoro-2-methyl-3-nitrophenyl)ethanone
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1-(2-Amino-3-fluorophenyl)ethanone hydrochloride
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1-(3-Fluoro-2-(trifluoromethyl)phenyl)ethanone
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1-(5-Fluoro-2-hydroxy-3-nitrophenyl)ethanone
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