Home Chemistry Organic Building Blocks Bromides 1-Bromo-3-Nitrobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —Br,—NO2).
Sonogashira Coupling: Bromobenzene can undergo coupling reactions with terminal 【alkynes|https://www.ambeed.com/alkynyls.html】 using a palladium catalyst, leading to the formation of substituted 【alkynes|https://www.ambeed.com/alkynyls.html】.
Sulfonation: Nitrobenzene can be sulfonated to introduce a sulfonic acid group (-SO3H) onto the benzene ring. Sulfonation is carried out using concentrated sulfuric acid, which leads to the substitution of one of the hydrogen atoms on the ring.
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1-Bromo-2-chloro-5-methoxy-3-nitrobenzene
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2-Bromo-4-nitro-1-(trifluoromethyl)benzene
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Methyl 2-(4-bromo-2-nitrophenyl)-2-(hydroxyimino)acetate
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1-(5-Bromo-2-hydroxy-3-nitrophenyl)ethanone
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Methyl 5-amino-4-bromo-2-nitrobenzoate
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Methyl 3-bromo-4-fluoro-5-nitrobenzoate
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