Home Chemistry Organic Building Blocks Fluorinated Building Blocks 1-Fluoro-3-Methoxybenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—OCH3).
Fluorine Substitution: Fluorobenzene can undergo further substitution reactions to replace the fluorine atom with other functional groups. This can be achieved through nucleophilic aromatic substitution reactions. The electron-withdrawing nature of fluorine can affect the regioselectivity and reactivity of such substitutions.
Borohydride Demethylation: Methoxybenzene can undergo demethylation reactions using sodium borohydride (NaBH4) in the presence of a proton source, resulting in the formation of phenol.
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(3,4-Difluoro-2-methoxyphenyl)boronic acid
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(S)-2-Amino-2-(3-fluoro-5-methoxyphenyl)ethanol
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(R)-2-Amino-2-(3-fluoro-5-methoxyphenyl)ethan-1-ol
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(R)-1-(2-Fluoro-4-methoxyphenyl)ethanamine hydrochloride
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(S)-1-(2-Fluoro-6-methoxyphenyl)ethanamine hydrochloride
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2-(Bromomethyl)-1-fluoro-3-methoxybenzene
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1-Bromo-4-fluoro-5-isopropyl-2-methoxybenzene
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