Home Chemistry Heterocyclic Building Blocks Pyrrolidines (S)-2-Benzhydrylpyrrolidine
Nucleophilic Substitution: If there are suitable leaving groups (e.g., halogens like Cl or Br) on the molecule, nucleophilic substitution reactions can occur. For example, you can replace a leaving group with a nucleophile like hydroxide ion (OH-) or amine.
Acid-Base Reactions: The pyrrolidine nitrogen can act as a base, reacting with strong acids to form salts. For example, it can react with HCl to form the corresponding hydrochloride salt.
Reduction: If there are functional groups like ketones or aldehydes present in the molecule, they can be reduced to alcohols using reducing agents like lithium aluminum hydride (LiAlH4) or sodium borohydride (NaBH4).
Oxidation: Conversely, if there are alcohols present in the molecule, they can be oxidized to ketones or aldehydes using oxidizing agents like chromic acid (H2CrO4) or potassium permanganate (KMnO4).
Ring Opening: If the conditions are suitable, the pyrrolidine ring can undergo ring-opening reactions to form linear or branched compounds.
Substitution Reactions: Depending on the substituents on the benzhydryl group, various substitution reactions can occur. For example, if there are halogens present, they can be substituted with other groups through appropriate reactions.
Addition Reactions: If there are unsaturated bonds in the molecule (e.g., double bonds), addition reactions can occur. For instance, you can add hydrogen gas (H2) to reduce double bonds.
Rearrangement Reactions: Rearrangement reactions can occur if there are suitable functional groups and conditions that promote rearrangements of the molecule's structure.
Catalytic Reactions: Depending on the catalyst used, various catalytic reactions may occur. For instance, palladium-catalyzed cross-coupling reactions with aryl halides are common in organic synthesis.
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