Home Chemistry Organic Building Blocks Phenols 2-Chloro-4-Fluorophenol
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Cl,—OH,—F).
Grignard Reaction: Chlorobenzene can react with magnesium metal to form phenylmagnesium chloride, which can then react with various electrophiles to introduce new functional groups onto the aromatic ring.
Phenol-Formaldehyde Resin Formation: Phenol can react with formaldehyde to form phenol-formaldehyde resins, commonly known as Bakelite and other similar materials.
Electrophilic Aromatic Substitution (EAS): Fluorobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The fluorine atom, being electron-withdrawing, can influence the reactivity of the benzene ring. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
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2-Chloro-6-fluoro-3-hydroxyphenylboronic acid
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